Abstract:fluoropyrimidines, platinum agents, and taxanes. Among them, one patient achieved confirmed partial response, and five pts showed stable disease. The most common treatment-related adverse events (!20% of pts) were rash (60%), anemia (30%), neutropenia (30%), thrombocytopenia (20%), and decreased appetite (20%). The second stage is ongoing. Conclusion: TAS-114 with S-1 showed a preliminary efficacy signal with acceptable safety profiles for heavily pretreated pts with AGC, which would be further confirmed in th… Show more
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