Prognostic factors for patients in postoperative brain metastases from surgically resected non-small cell lung cancer

Abstract

Our study found that the foregoing clinical characteristics in postoperative brain metastases and the administration of treatment contributed to patient life expectancy.

Prognostic factors for cases with no extracranial metastasis in whom brain metastasis is detected after resection of non-small cell lung cancer

“…In addition, adenocarcinoma showed a longer disease-free interval and better postrecurrence survival than non-adenocarcinoma. The results agreed with other studies [7,8,[10][11][12].…”

“…According to the report of Sakamoto et al, 6.7% (65/967) of lung cancer patients developed postoperative brain metastases, and 3.2% (31/967) of patients had only brain metastasis as the initial postoperative recurrence [7]. The postrecurrence survival of these patients also showed results to other reported studies.…”

“…However, there was no difference in postrecurrence survival in relation to the stage or nodal status of the initial lung cancer. Other studies have shown similar findings [7,[15][16][17]. Thus, while the initial lung cancer stage can be a good predictor for recurrence after surgery, it may not be a predictor for postrecurrence survival.…”

“…According to the study of Rodrigus presenting with one or more extracranial metastases [2]. Sakamoto et al also reported that patients with only brain metastases as the postoperative initial recurrence had better prognosis than the patients combined with extracrainal metastases [7]. Moasami et al evaluated patients with metachronous brain metastasis as stage IIIa NSCLC.…”

Surgical management of oligometastatic non-small cell lung cancer

“…They can be detected up to 30% to 55% of the cases at autopsy (28). Sakamoto et al (29) reported that 3.2% of the patients will develop only metachronous brain metastasis after surgery for the primary tumor. The survival after recurrence is poor.…”