Prognostic factors for survival after surgery for adrenal metastasis

Muth, Andreas; Persson, Fredrik; Jansson, Svante; Johanson, Viktor; Ahlman, Håkan; Wängberg, Bo

doi:10.1016/j.ejso.2010.04.002

Cited by 94 publications

(82 citation statements)

References 17 publications

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“…However, in cases of isolated adrenal metastases survival can be improved after adrenalectomy [3,[11][12][13]. In our 19 patients with isolated adrenal metastases, the mean estimate survival was 25.0 months, which according to the results of other authors [6,[15][16][17]. Xin Ma et al [18] have reported median estimate survival of 24 months, and 5-year survival of 6.1% in a group of 75 patients with adrenal metastases.…”

Section: Discussionsupporting

confidence: 63%

“…In our patients we found no statistical difference between tumour size and overall survival (log-rank test; p=0.621), i.e. it was not to be a prognostic factor, as other authors have established in their studies and analyses [6,14,16,17].…”

Section: Discussionmentioning

confidence: 58%

“…According to Lo et al [3], patients with metastases from an adenocarcinoma had a better chance of survival. Muth et al [17] have reported that patients with colorectal carcinoma have better outcomes than those with NSCLC. According to Paunovic et al [8] the type of primary tumour does not influence survival.…”

Section: Discussionmentioning

confidence: 99%

“…According to certain authors [3, 17,18], there was no significant survival between patients with synchronous and patients with metachronous metastases. According to other reports [6,14,15,20], patients with metachronous metastases had better survival than those with synchronous.…”

Section: Discussionmentioning

confidence: 99%

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Adrenalectomy for Isolated Metastases

Shumarova¹,

Petrov²,

Grozdev³

et al. 2017

JofIMAB

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Background: Isolated adrenal gland metastases are not frequently finding. The aim of the present retrospective study was to estimate clinical and pathological parameters that could be used to predict survival after adrenalectomy.Material and methods: A total of 34 patients with adrenal gland masses suspected to be metastases was included in this study. The group of patients with isolated metastases was19 (56%) and a group of patients with adrenal adenomas -15 (44%).Results: The sample of patients consisted of 18 (53%) men and 16 (47%) women from 40 to 81 years old with a mean (±SD) age of 61.6±10.3 years, presented with adrenal mass suspected to be metastases. Nineteen (56%) of them had demonstrated metastases and 16 (84%) metachronous with median overall survival (OS) 54.6 (range 43-66) months. Median OS in the group with metastases was 22.6 months. Lung carcinoma was the most common primary tumour metastasizing in the adrenal gland -58% of all metastases with a disease-free interval (DFI) of 13 months. It was presented by shorter median survival than the rest primary tumour types (37.8 vs. 96.7months; logrank test, p=0.028). In the multivariate Cox's hazard analysis of the surgical technique was found to be an independent prognostic factor (p=0.047), together with lung carcinoma vs. renal cell carcinoma (p=0.045).Conclusion: Adrenalectomy due to isolated metastases in the adrenal glands showed the median overall survival of 22.6 months. Shorter survival periods were associated with lung carcinoma, DFI<12months, conversion to open surgery, synchronous metastases, but not with age, tumour size or resection status.

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Section: Discussionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 58%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Adrenalectomy for Isolated Metastases

Shumarova¹,

Petrov²,

Grozdev³

et al. 2017

JofIMAB

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show abstract

“…[7], посвященной прогностиче-ским факторам долгосрочной выживаемости, проанализирован опыт выполнения адреналэктомии у 30 больных по поводу мета-стазов опухолей различной локализации. Отмечено, что благо-приятным прогностическим фактором является возникновение метастатического поражения надпочечника в сроки не менее 12 мес после удаления первичной опухоли, неблагоприятным фактором -наличие в анамнезе у больных оперативных вмеша-тельств по поводу метастазов различной локализации.…”

Section: хирургия 1 2015unclassified