Prognostic factors in surgically resected pulmonary pleomorphic carcinoma

Kaminuma, Yasunori; Tanahashi, Masayuki; Yukiue, Haruhiro; Suzuki, Eriko; Yoshii, Naoko; Kitazawa, Shinsuke; Niwa, Hiroshi

doi:10.2995/jacsurg.32.556

Cited by 2 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 7 - 10) In addition, the 5-year DFS was reported as 33.6%–63.3%. 9 - 11) Our results are similar to those of past reports but less than those reported recently.…”

Section: Discussionsupporting

confidence: 89%

“…and pathological findings (pathological stage, lymph node metastasis, tumor size, etc.). 6 - 11) In this study, DFI within 1 year was detected as a poor prognostic factor for OS, and the N2 pathological status and presence of adenocarcinoma components were identified as poor prognostic factors for DFS. We could not identify significant differences in the survival curves for tumor size, stage, and v-factor that were previously reported to have poor prognosis.…”

Section: Discussionmentioning

confidence: 61%

“… 13) Similar results were found in our study. Recently, Kaminuma et al 11) reported that a high concentration of FDG PET-CT is a prognostic factor of OS and DFS and that FDG accumulation reflects tumor malignancy. However, in our study, SUV max values were not extracted as shown to be prognostic predictors.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinicopathological Analysis of 17 Surgically Resected Pulmonary Pleomorphic Carcinoma Cases

Iijima

Nakajima

Kinoshita

et al. 2021

ATCS

View full text Add to dashboard Cite

Objectives: To determine the outcomes and prognostic factors associated with pulmonary resection of pulmonary pleomorphic carcinoma (PPC). Methods: During 2008–2017, 17 patients underwent pulmonary resection for primary PPC at the Saitama Cancer Center, Japan. We investigated clinicopathological characteristics and outcomes of these cases. Overall survival (OS) and disease-free survival (DFS) rates were determined using Kaplan–Meier method and compared using log-rank test. Univariate analysis was performed to identify prognostic factors. Results: The 5-year OS and DFS rates were 27.2% and 51.0%, respectively. The median follow-up period was 30.8±24.9 (3.6–92.8) months after pulmonary resections. Patients with disease-free interval (DFI) <1 year of resection had poorer prognosis than those without (p = 0.001). Patients with N2 status and adenocarcinoma components had significantly poorer disease-free prognosis than their counterparts (p = 0.021 and p = 0.019, respectively). Univariate analysis revealed that DFI <1 year was an unfavorable prognostic factor for OS (p = 0.005); N2 pathological status and presence of adenocarcinoma components were unfavorable prognostic factors for DFS (p = 0.038 and p = 0.036, respectively). Conclusion: PPC patients with an adenocarcinoma component and N2 pathological status may have an earlier relapse and poorer prognosis than their counterparts. Further assessment of cases may help clarify the predictors of PPC.

show abstract

“… 7 - 10) In addition, the 5-year DFS was reported as 33.6%–63.3%. 9 - 11) Our results are similar to those of past reports but less than those reported recently.…”

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 61%

See 1 more Smart Citation

Clinicopathological Analysis of 17 Surgically Resected Pulmonary Pleomorphic Carcinoma Cases

Iijima

Nakajima

Kinoshita

et al. 2021

ATCS

View full text Add to dashboard Cite

show abstract

“…and pathological findings (pathological stage, lymph node metastasis, tumor size, etc.) [2][3][4][5][6][7][8]. However, the prognostic factors for stage IV PPC are not clear.…”

Section: Discussionmentioning

confidence: 99%

A case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatment

et al. 2020

View full text Add to dashboard Cite

Background: Generally, primary pulmonary pleomorphic carcinoma is resistant to treatment and has a poor prognosis. We report a case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatment. Case presentation: A 74-year-old man with a history of emphysema, pneumoconiosis, and chronic bronchitis presented with left lung nodule and left adrenal tumor based on computed tomography. We suspected clinical T1bN0M1b, stage IVB lung cancer. Adrenalectomy of the left adrenal tumor yielded a definitive diagnosis of pleomorphic carcinoma. Chemotherapy was performed despite the spontaneous regression of lung lesions. Since lung lesions re-enlarged 11 months after adrenalectomy, the left lower lobe was partially resected followed by chemotherapy. The lung lesion was the primary lesion of the adrenal tumor. There was no recurrence 100 months after the lung resection. Conclusions: The patient experienced long-term survival after multidisciplinary treatment. Both multidisciplinary treatment and immunological mechanisms caused spontaneous regression of the primary lesion.

show abstract

Prognostic factors in surgically resected pulmonary pleomorphic carcinoma

Cited by 2 publications

References 17 publications

Clinicopathological Analysis of 17 Surgically Resected Pulmonary Pleomorphic Carcinoma Cases

Clinicopathological Analysis of 17 Surgically Resected Pulmonary Pleomorphic Carcinoma Cases

A case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatment

Contact Info

Product

Resources

About