Prognostic factors of Bell's palsy and Ramsay Hunt syndrome

Abstract

The aim of this study was to compare clinical characteristics, electroneurography (ENoG) results, and functional outcomes of patients with Bell's palsy (BP) and Ramsay Hunt syndrome (RHS).Around 57 patients with BP and 23 patients with RHS were enrolled in this study from January 2010 and September 2015. Both clinical characteristics and ENoG results were recorded at hospital admission. The evaluations of functional outcomes were conducted with House–Brackmann (H-B) grading system at 6-month follow-up.There were no significant differences in age, gender proportion, initial H-B grades, time before commencement of treatment and the presence of comorbid disease in 2 groups. However, the final H-B grades at 6-month follow-up were significantly better in BP patients than RHS patients. The results of ENoG showed that degeneration index (DI) was significantly higher in the RHS group than the BP group. But no significant difference was found in the value of prolonged latency time (PLT) between the 2 groups. In multivariate analysis, age and ENoG DI were independently associated with functional outcome of recovery in the BP group (OR 0.167, 95% CI 0.038–0.622, P = 0.009 and OR 0.289 95% CI 0.107–0.998, P = 0.050, respectively). However, in the RHS group, only ENoG DI was related to the final H-B grades (OR 0.067, 95% CI 0.005–0.882, P = 0.040). Spearman's rank correlation analysis showed that higher age and ENoG DI were related to poorer prognosis in 2 groups (P < 0.05). PLT was related to functional outcomes only in the BP group (rs = 0.460, P < 0.001). The receiver operating characteristic (ROC) of ENoG DI analysis revealed that the cutoff value was 67.0% for BP prognosis and 64.5% for RHS prognosis. What's more, patients with hypertension or diabetes mellitus had both higher final H-B grade and ENoG DI than those without the same comorbidity.Patients with RHS had poorer prognosis than those with BP. Some factors including age, ENoG DI, and the presence of disease influenced recovery from BP and RHS. The present study demonstrated that BP patients with ENoG DI < 67.0% and RHS patients with ENoG DI < 65.5% had a greater opportunity for recovery within half a year.

Prognostic Factors of Idiopathic Facial Palsy: A Retrospective Study

“…However, the results of this study differ from previous studies undertaken in Korea [18][19][20][21] that a history of diabetes mellitus and hypertension is not significant in the prognosis of facial palsy. However, the results of this study showing that hypertension, diabetes mellitus are statistically significant with the prognosis of facial palsy are consistent with studies from other countries 16,17) . Further research is needed on this matter.…”

The Implication of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio between Diabetic and Non-Diabetic Bell’s Palsy Patients

“…The incidence of AFP in the literature is found to be 30/100,000, and the most common causes are BP and RHS. [1,3] The etiopathogenesis of BP is still unclear. Infection, genetic factors, microvascular circulatory impairment, immunological factors, and inflammation have been blamed.…”

“…The incidence of AFP is found to be 30/100,000 in the literature. [1] It can be caused by many diseases, such as cancer, trauma, Bell's palsy (BP), Ramsay Hunt syndrome (RHS), and iatrogenic injury. [1,2] The most common causes among these are BP and RHS.…”

“…[1] It can be caused by many diseases, such as cancer, trauma, Bell's palsy (BP), Ramsay Hunt syndrome (RHS), and iatrogenic injury. [1,2] The most common causes among these are BP and RHS. [1,3] The incidence of BP is 15-30/100,000 in the literature.…”

“…[1,2] The most common causes among these are BP and RHS. [1,3] The incidence of BP is 15-30/100,000 in the literature. [4] The etiology of the disease is not clear, but vascular causes, autoimmune diseases, and inflammation of the nerve sheath are indicated in the pathogenesis.…”