Prognostic factors related to clinical outcome following thrombectomy in ischemic stroke (RECOST Study). 50 patients prospective study

Costalat, Vincent; Lobotesis, Kyriakos; Machi, Paolo; Mourand, Isabelle; Maldonado, Igor Lima; Héroum, C.; Vendrell, Jean-François; Milhaud, D.; Riquelme, Carlos; Bonafé, Alain; Arquizan, Caroline

doi:10.1016/j.ejrad.2012.07.012

Cited by 82 publications

(66 citation statements)

References 22 publications

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“…These findings are consistent with those of several previous studies that evaluated the independent predictors of clinical outcome after mechanical thrombectomy in patients with acute ischemic stroke owing to intracranial large vessel occlusion, which found that a younger age, lower NIHSS score on admission, successful revascularization, and shorter procedure time were independent predictors of good outcom. [7][8][9][10] Here, incomplete revascularization was significantly associated with a poor clinical outcome. Several previous studies examined or mentioned potential differences in outcome between patients with a TICI of 3 versus a TICI of 2b.…”

Section: Discussionmentioning

confidence: 99%

“…For example, Costalat et al reported that the baseline NIHSS score was an independent predictor of poor outcome at 3 months after treatment. 9 Similarly, Jiang et al showed that fewer patients with baseline NIHSS scores < 20 had a good outcome compared with those exhibiting NIHSS scores ! 20.…”

Section: Discussionmentioning

confidence: 99%

“…Of the 69 included patients, 35 (50.7%) had atrial fibrillation, 36 (52.2%) had hypertension, and 15 (21.7%) had diabetes mellitus. The patients' mean DWI-ASPECTS was 7.5 (range, [3][4][5][6][7][8][9][10][11]. Among the 69 patients, the occluded vessel was the ICA in 24 patients (34.8%), the MCA M1 portion in 41 patients (59.4%), and the MCA M2 portion in 4 patients (5.8%).…”

Section: Baseline Characteristics Of the Patientsmentioning

confidence: 99%

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Predictors of Poor Outcome after Successful Mechanical Thrombectomy in Patients with Acute Anterior Circulation Stroke

Tajima

Hayasaka

Ebihara

et al. 2017

J Clin Interv Radiol ISVIR

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Successful revascularization is one of the main predictors of a favorable clinical outcome after mechanical thrombectomy. However, even if mechanical thrombectomy is successful, some patients have a poor clinical outcome. This study aimed to investigate the clinical, imaging, and procedural factors that are predictive of poor clinical outcomes despite successful revascularization after mechanical thrombectomy in patients with acute anterior circulation stroke. The authors evaluated 69 consecutive patients (mean age, 74.6 years, 29 women) who presented with acute ischemic stroke due to internal cerebral artery or middle cerebral artery occlusions and who were successfully treated with mechanical thrombectomy between July 2014 and November 2016. A good outcome was defined as a modified Rankin Scale score of 0 to 2 at 3 months after treatment. The associations between the clinical, imaging, and procedural factors and poor outcome were evaluated using logistic regression analyses. Using multivariate analyses, the authors found that the preoperative National Institute of Health Stroke Scale (NIHSS) score (odds ratio [OR], 1.152; 95% confidence interval [CI], 1.004–1.325; p = 0.028), the diffusion-weighted imaging Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) (OR, 0.604; 95% CI, 0.412–0.882; p = 0.003), and a Thrombolysis in Cerebral Infarction (TICI) 2b classification (OR, 4.521; 95% CI, 1.140–17.885; p = 0.026) were independent predictors of poor outcome. Complete revascularization to reduce the infarct volume should be performed, especially in patients with a high DWI-ASPECTS, to increase the likelihood of a good outcome.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Baseline Characteristics Of the Patientsmentioning

confidence: 99%

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Predictors of Poor Outcome after Successful Mechanical Thrombectomy in Patients with Acute Anterior Circulation Stroke

Tajima

Hayasaka

Ebihara

et al. 2017

J Clin Interv Radiol ISVIR

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“…A variety of studies have shown that NIHSS is an independent predictor of outcome at 90 days for both intra-arterial thrombolysis (IAT) and thrombectomy [29][30][31]. It has also been shown that higher NIHSS is associated with higher rates of futile recanalization [20] and haemorrhage [32].…”

Section: Differences In Factors Predicting Outcome and Mortality Aftementioning

confidence: 99%

Differences in Factors Predicting Outcome and Mortality after Mechanical Thrombectomy for Acute Large Vessel Stroke Between Patients over and Under 70 Years of Age: A Five Year Retrospective Study

Nayak¹

2015

SOJN

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“…The MCA occlusion post-thrombectomy outcome is comparable with the outcome of RECOST study. [19] In AIS, good outcome following successful recanalization is time dependent. [20] Patients with faster recanalization with less number of passes with Solitaire had a good outcome.…”

Section: Clinical Outcomementioning

confidence: 99%

Safety and efficacy of mechanical thrombectomy with Solitaire in patients with acute ischemic stroke

Narayana¹,

Pati²,

Dalai³

2017

IJNS

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Background Stroke is the third most common cause of death. Ischemic stroke accounts for 87% of all strokes. The standard treatment for acute ischemic stroke (AIS) is IV recombinant tissue plasminogen activator for patients who can reach the hospital with in 4.5 h. A rapid and complete recanalization is a major factor in good clinical outcomes in the treatment of acute cerebral ischemia. Stent-based recanalization techniques are increasingly used in stroke caused by large vessel occlusion, with promising results. Objective To evaluate the safety and efficacy of Solitaire stent retriever in recanalizing cerebral vessels in patients with AIS. Materials and Methods We treated 16 patients of AIS with a mean age of 52.25 years, ranging from 16 to 76 years with Solitaire clot retrieval system from September 2011 to March 2013 at our stroke center. The anterior circulation strokes were treated within 6 h of stroke onset and the posterior circulation strokes were treated up to 24 h of stroke onset. Patients with intracerebral bleed and established large acute infarcts were excluded. Results Out of the 16 patients of AIS treated with Solitaire clot retrieval system, good recanalization (thrombolysis in cerebral infarction 2 [TICI 2] and TICI 3) was achieved in 14/16 patients (87.5%) and no recanalization achieved in 2/16 (12.5%) patients. Clinical outcome was good (modified Rankin score 2 or less) in 10 out of 16 patients (62.5%). Conclusion Mechanical clot retrieval with Solitaire appears to be safe and effective in acutely occluded large intracranial vessels.

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Prognostic factors related to clinical outcome following thrombectomy in ischemic stroke (RECOST Study). 50 patients prospective study

Cited by 82 publications

References 22 publications

Predictors of Poor Outcome after Successful Mechanical Thrombectomy in Patients with Acute Anterior Circulation Stroke

Predictors of Poor Outcome after Successful Mechanical Thrombectomy in Patients with Acute Anterior Circulation Stroke

Differences in Factors Predicting Outcome and Mortality after Mechanical Thrombectomy for Acute Large Vessel Stroke Between Patients over and Under 70 Years of Age: A Five Year Retrospective Study

Safety and efficacy of mechanical thrombectomy with Solitaire in patients with acute ischemic stroke

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