Prognostic relevance of peri-infarct zone measured by cardiovascular magnetic resonance in patients with ST-segment elevation myocardial infarction

Jensch, Philipp-Johannes; Stiermaier, Thomas; Reinstadler, Sebastian Johannes; Feistritzer, Hans‐Josef; Desch, Steffen; Fuernau, Georg; Waha‐Thiele, Suzanne de; Thiele, Holger; Eitel, Ingo

doi:10.1016/j.ijcard.2021.11.017

Cited by 8 publications

(4 citation statements)

References 21 publications

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“…According to Jensch P.J. et al, PIZ volume > 14 mL was considered a predictor of major adverse cardiovascular events such as death, recurrent MI, and congestive heart failure within one year after MI [ 17 ]. According to Jones R.E.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Magnetic Resonance Imaging Based Ischemic Injury Pattern in Patients with Acute Myocardial Infarction Sensu Left Ventricular Global Systolic Function

Salyamova,

Oleynikov,

Donetskaya

et al. 2024

Diagnostics

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The purpose of the study was to identify factors characterizing a decrease in LV global systolic function in patients with ST-segment elevation myocardial infarction (STEMI) after revascularization using cardiac magnetic resonance imaging (MRI)-based ischemic injury pattern and laboratory parameters sensu left ventricular global systolic function. A total of 109 STEMI patients were examined. The patients underwent contrast-enhanced cardiac MRI with a 1.5 Tesla GE SIGNA Voyager (GE HealthCare, Chicago, IL, USA) on the 7th–10th days from the onset of the disease. According to cardiac MRI analysis, the patients were divided into the following groups with regard to left ventricular ejection fraction (LVEF) values: Group 1—patients with LVEF ≥ 50%; group 2—patients with mildly reduced LVEF 40–49%; group 3—patients with low LVEF < 40%. A predominance of most parameters of the ischemic injury pattern was noted in patients with mildly reduced and low LVEF versus patient group with LVEF ≥ 50%. Some risk factors for a decrease in LVEF < 50% systolic function in STEMI patients after revascularization were revealed: male gender; time from the onset of the anginal attack to revascularization; coronary artery status; several LV parameters; ischemic injury characteristics; natriuretic peptide and troponin I levels.

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Section: Discussionmentioning

confidence: 99%

Cardiac Magnetic Resonance Imaging Based Ischemic Injury Pattern in Patients with Acute Myocardial Infarction Sensu Left Ventricular Global Systolic Function

Salyamova,

Oleynikov,

Donetskaya

et al. 2024

Diagnostics

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“…По данным Jensch PJ, et al (2022), объем ПГЗ >14 мл являлся предиктором серьезных неблагоприятных сердечных событий, таких как смерть, повторный инфаркт миокарда, застойная сердечная недостаточность в течение одного года после ОИМ. Таким образом, данный показатель является потенциальным маркером для стратификации риска у пациентов с инфарктом миокарда с подъемом сегмента ST (ИМпST) [10].…”

Section: Discussionunclassified

Effect of ischemic injury characteristics on left ventricular systolic function in patients with acute myocardial infarction

Oleinikov,

Salyamova,

Donetskskaya

et al. 2023

Russ J Cardiol

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Aim. To study laboratory and magnetic resonance imaging (MRI) characteristics of infarction area depending on left ventricular (LV) global systolic function in patients with acute myocardial infarction (AMI) after revascularization.Material and methods. A total of 78 patients with primary AMI were included. On days 7-10, contrast-enhanced cardiac MRI was performed. Blood brain natriuretic peptide (BNP) was analyzed. Cardiac MRI was used to determine the characteristics of scar tissue, peri-infarct zone (PIZ), microvascular obstruction (MVO), intramyocardial hemorrhage (IMH) and the global contrast index.Results. According to the MRI, patients were divided into following groups: group 1 — LV ejection fraction (LVEF) ≥50% (n=50), group 2 — LVEF 40-49% (n=21), group 3 — LVEF <40% (n=7).The BNP in groups 1, 2, 3 was 106,8 (37,5; 248), 232,6 (170,1; 337,7) and 548,5±236,4 ng/ml, respectively (p1-3<0,05). The scar tissue mass in groups 1, 2, 3 was 10,3 (2,4; 20,0), 34,7±21,3, 59,4±37,6 g, respectively (p1-2, 3<0,01). PIZ differences were found only between patients with preserved and mildly reduced EF. MVO was diagnosed in 26% of patients with LVEF ≥50%, in 47,6% of patients with LVEF of 40-49% and 85,7% with LVEF <40% (p1-3<0,01). The detection rate of IMH prevailed in the 2nd group (33,3%) compared with the 1st group (12%) (p1-2<0,05). The global contrast index was the lowest in the 1st group (14,7 (8,8; 27,9)%), intermediate in the 2nd group (33,3±12,6%), the highest in the 3th group (54,2±19,5%) (р1-2, 3; 2-3<0,05).Conclusion. The following risk factors for a decrease in LV systolic function in patients with AMI after revascularization were identified: the size of scar tissue, PIZ, MVO and IMH characteristics, global contrast index, BNP level.

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“…Cluster 3 (dark blue) primarily involves researchers like Thiele, Holger from Germany, Eitel, Ingo from Germany, and Stone, Gregg W. from the United States. Their main collaborative research explores using imaging techniques (such as cardiac magnetic resonance, CMR) to predict the risk of subsequent heart failure post-MI [31][32][33] and also covers the e cacy of bone marrow-derived monocytes [34], percutaneous coronary intervention (PCI) [35,36], and remote ischemic preconditioning [37] for post-MI HF.…”

Section: Distribution Of Authorsmentioning

confidence: 99%

Research status and development trends of post-myocardial infarction heart failure: a bibliometric analysis from 2012 to 2022

Hou,

Wang,

et al. 2024

Preprint

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Objective: Post-myocardial infarction heart failure (post-MI HF) is a prevalent cardiovascular disease. The study aims to preliminarily explore the current research status and development trends in the field of post-MI HF, providing reference ideas and methods for clinical and scientific research. Methods: Publications related to post-MI HF from 2012-2022 in the Web of Science Core Collection's SCI-expanded dataset were extracted. Bibliometric analysis was executed using VOSviewer and R-bibliometrix, encompassing the number of publications, countries, institutions, authors, journals, cited references, and keywords. Results: Within the last decade, 10,929 publications in the domain were published, involving 58,357 authors from 10,437 research institutions across 120 different countries and regions. These findings appeared in 1,446 distinct journals. The United States led in the number of publications, with Harvard Medical School being the most active institution and Kober, Lars from the University of Copenhagen, Denmark, as the leading author. Plos One was the most prolific journal, while Circulationhad the highest citation count. Over the past decade, research hotspots mainly centered on mortality, cardiac remodeling, and prognosis. In the recent two years, emphasis shifted to topics such as mendelian randomization, dapagliflozin, sacubitril/valsartan, COVID-19, and machine learning. Conclusion: The study reveals the overall performance of publications in the post-MI HF research field. The clinical prognosis of patients and cardiac remodeling have been research hotspots over the past decade, yet mortality and readmission remain urgent clinical challenges. Future research trends in this field may revolve around the mechanisms of cardiac remodeling, apoptosis, and inflammation, as well as clinical prognosis studies on patient mortality rates. Additionally, echocardiography and cardiac magnetic resonance technology are gradually becoming important methods for evaluating drug efficacy and elucidating related mechanisms.

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Prognostic relevance of peri-infarct zone measured by cardiovascular magnetic resonance in patients with ST-segment elevation myocardial infarction

Cited by 8 publications

References 21 publications

Cardiac Magnetic Resonance Imaging Based Ischemic Injury Pattern in Patients with Acute Myocardial Infarction Sensu Left Ventricular Global Systolic Function

Cardiac Magnetic Resonance Imaging Based Ischemic Injury Pattern in Patients with Acute Myocardial Infarction Sensu Left Ventricular Global Systolic Function

Effect of ischemic injury characteristics on left ventricular systolic function in patients with acute myocardial infarction

Research status and development trends of post-myocardial infarction heart failure: a bibliometric analysis from 2012 to 2022

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