Prognostic Risk Models Using Epithelial Cells Identify β-Sitosterol as a Potential Therapeutic Target Against Esophageal Squamous Cell Carcinoma
Zhenhu Zhang,
Bin Shang,
Xinyu Mao
et al.
Abstract:Background
Esophageal squamous cell carcinoma (ESCC) is an aggressive and fatal malignancy that leads to epithelial cancer. The association between epithelial cell heterogeneity, prognosis, and immune response in this cancer remains uncertain. This study aimed to investigate epithelial cell heterogeneity in ESCC and develop a predictive risk model using the identified cell types.
Methods
Single-cell RNA sequencing (scRNA-seq) and differential ESCC gene data were accesse… Show more
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