Prognostic role of aortic atherosclerosis and coronary flow reserve in patients with suspected coronary artery disease

The independent long-term prognostic value of coronary flow velocity reserve in female patients with chest pain and negative coronary angiograms (Results from the SZEGED study)

“…Coronary flow velocity reserve (CFR) assessment on the left anterior descending coronary artery (LAD) by echocardiography is an excellent option for evaluating coronary microcirculatory abnormalities in the absence significant LAD stenosis [2,3]. Recently, the independent prognostic significance of CFR has been demonstrated in a number of diseases [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. The objective of the present study was to assess whether pulsed-wave Doppler echocardiography-derived CFR has a prognostic value for cardiovascular outcome in female patients with chest pain and normal epicardial coronary arteries.…”

Coronary flow velocity reserve predicts survival in non-diabetic patients

“…It is known that CFR is diminished in hypertension and the degree of CFR reduction is related to the extent of LV hypertrophy [34]. Moreover, prognostic value of echocardiography-derived CFR has even been demonstrated in hypertension [26]. These facts could highlight our attention on hypertension and its diagnostic and prognostic significance on survival, but could be considered as the main limitation of the current study, as well.…”

“…In a recent study, DM and CFR were independently predictive of cardiovascular survival in patients with known or suspected CAD [2]. The additive prognostic value of simultaneously evaluated CFR and wall motion abnormalities [3,[21][22][23][24], aortic distensibility indices [25], or grade of AA [26] was also demonstrated. Moreover, CFR was found to be predictive for future events in hypertensives [27], AS [6], dilated [28][29][30] and hypertrophic cardiomyopathies [5,31], in renal transplant recipients [32] and after heart transplantation [33], as well.…”

Non-Invasive Assessment of Coronary Blood Flow in Patients With 2nd Type Diabetes During Exercise Test

“…Измерение гемодинамического коронарного резерва (ГКР) с помощью допплерографии у паци-ентов с верифицированной или предполагаемой ишемической болезнью сердца (ИБС) используется при проведении фармакологических стресс-эхокар-диографических тестов (стресс-ЭхоКГ) для диагно-стики и определения уровня риска неблагоприятных исходов [1][2][3][4][5][6], что нашло отражение в рекоменда-циях экспертов [7]. Также была показана возмож-ность диагностики ИБС при измерении ГКР во время более безопасных и физиологичных тестов с физической нагрузкой (ФН) [8].…”