Prognostic Significance of Chest Imaging by LUS and CT in COVID-19 Inpatients: The ECOVID Multicenter Study

Tana, Claudio; Ricci, Fabrizio; Coppola, Maria Gabriella; Mantini, Cesare; Lauretani, Fulvio; Campanozzi, Daniele; Renda, Giulia; Gallina, Sabina; Lugarà, Marina; Cipollone, Francesco; Giamberardino, Maria Adele; Mucci, Luciano

doi:10.1159/000518516

Cited by 29 publications

(31 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Berce et al underline the importance of LUS as a useful method in a bacterial or viral outbreak or in epidemic times [ 30 ]. Lately, several studies have shown a significant role of LUS in the evaluation of COVID-19 pneumonia, not only regarding its accuracy in the detection of lesions, but also in evaluating the risk of death and complications development [ 8 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

“…Even if CT images present the highest accuracy, CT should not always be recommended for all children with COVID due to its significant irradiation potential. Furthermore, recent studies demonstrated a strong correlation between LUS and CT scores, proving that an ultrasound score higher than 20 (using 12-area score) is associated with an increased risk of complications and death [ 8 , 9 ]. As COVID-19 has become a worldwide disease, in many hospitals, the availability of CT scans for many patients diagnosed with COVID-19 is not widespread.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Is Lung Ultrasound Helpful in COVID-19 Neonates?—A Systematic Review

et al. 2021

View full text Add to dashboard Cite

Background: The SARS-CoV-2 infection has occurred in neonates, but it is a fact that radiation exposure is not recommended given their age. The aim of this review is to assess the evidence on the utility of lung ultrasound (LUS) in neonates diagnosed with COVID-19. Methods: A systematic literature review was performed so as to find a number of published studies assessing the benefits of lung ultrasound for newborns diagnosed with COVID and, in the end, to make a comparison between LUS and the other two more conventional procedures of chest X-rays or CT exam. The key terms used in the search of several databases were: “lung ultrasound”, “sonography”, “newborn”, “neonate”, and “COVID-19′. Results: In total, 447 studies were eligible for this review, and after removing the duplicates, 123 studies referring to LU were further examined, but only 7 included cases of neonates. These studies were considered for the present research paper. Conclusions: As a non-invasive, easy-to-use, and reliable method for lung lesion detection in neonates with COVID-19, lung ultrasound can be used as a useful diagnosis tool for the evaluation of COVID-19-associated lung lesions. The benefits of this method in this pandemic period are likely to arouse interest in opening new research horizons, with immediate practical applicability.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Is Lung Ultrasound Helpful in COVID-19 Neonates?—A Systematic Review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Descriptive data on LUS artefacts in a number of conditions have been published, but the development of LUS scores has opened the door to objective evaluation. These studies show a correlation between LUS scores and inflammation [ 29 ], lung function in CF, and even mortality prognosis [ 43 ] in several diseases.…”

Section: Discussionmentioning

confidence: 99%

Lung Ultrasound in Children with Cystic Fibrosis in Comparison with Chest Computed Tomography: A Feasibility Study

et al. 2022

View full text Add to dashboard Cite

Background: Cystic fibrosis (CF) lung disease determines the outcome of this condition. For lung evaluation processes, computed tomography (CT) is the gold standard, but also causes irradiation. Lately, lung ultrasound (LUS) has proven to be reliable for the diagnosis of consolidations, atelectasis, and/or bronchiectasis. The aim of our study was to evaluate the value of a newly conceived LUS score by comparing it to the modified Bhalla CT score. A further aim was to evaluate the correlation between the score and the lung clearance index (LCI). Methods: Patients with CF were screened by LUS, followed by a CT scan. Spearman’s test was used for correlations. Results: A total of 98 patients with CF were screened, and 57 were included in the study; their mean age was 11.8 ± 5.5 (mean ± SD) years. The mean LUS score was 5.88 ± 5.4 SD. The LUS CF score had a very strong correlation with the CT score of rs = 0.87 (p = 0.000). LUS showed a good sensibility for detecting atelectasis (Se = 83.7%) and consolidations (Se = 94.4%). A lower Se (77.7%) and Sp (9%) were found for cylindrical bronchiectasis. Conclusion: Our study shows that LUS and the lung CF score are parameters that can be used with a complementary role in the diagnosis and monitoring of CF lung disease in children.

show abstract

“…A growing body of evidence indicates that some diagnostic tools, including the lung ultrasound (LUC) may present some usefulness in diagnosis, optimization of treatment, and risk stratification in COVID-19 patients [ 30 , 31 , 32 ]. Therefore, a multidimensional assessment of risk factors for an unfavorable outcome of COVID-19, including the data from imaging diagnostics, could constitute an interesting approach.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of C2HEST Score in Predicting Clinical Outcomes of COVID-19 in Heart Failure and Non-Heart-Failure Cohorts

Rola¹,

Doroszko

Trocha

et al. 2022

JCM

View full text Add to dashboard Cite

Background: Patients with heart failure represent a vulnerable population for COVID-19 and are prone to having worse prognoses and higher fatality rates. Still, the clinical course of the infection is dynamic, and complication occurrence in particular in patients with heart failure is fairly unpredictable. Considering that individual components of the C2HEST (C2: Coronary Artery Diseases (CAD)/Chronic obstructive pulmonary disease (COPD); H: Hypertension; E: Elderly (Age ≥ 75); S: Systolic HF; T: Thyroid disease) are parallel to COVID-19 mortality risk factors, we evaluate the predictive value of C2HEST score in patients with heart failure (HF) Material and Methods: The retrospective medical data analysis of 2184 COVID-19 patients hospitalized in the University Hospital in Wroclaw between February 2020 and June 2021 was the basis of the study. The measured outcomes included: in-hospital mortality, 3-month and 6-month all-cause-mortality, non-fatal end of hospitalization, and adverse in-hospital clinical events. Results: The heart failure cohort consists of 255 patients, while 1929 patients were assigned to the non-HF cohort. The in-hospital, 3-month, and 6-month mortality rates were highest in the HF cohort high-risk C2HEST stratum, reaching 38.61%, 53.96%, and 65.36%, respectively. In the non-HF cohort, in-hospital, 3-month, and 6-month mortalities were also highest in the high-risk C2HEST stratum and came to 26.39%, 52.78%, and 65.0%, respectively. An additional point in the C2HEST score increased the total death intensity in 10% of HF subjects (HR 1.100, 95% CI 0.968–1.250 p = 0.143) while in the non-HF cohort, the same value increased by 62.3% (HR 1.623, 95% CI 1.518–1.734 p < 0.0001). Conclusions: The C2HEST score risk in the HF cohort failed to show discriminatory performance in terms of mortality and other clinical adverse outcomes during hospitalization. C2HEST score in the non-HF cohort showed significantly better performance in terms of predicting in-hospital and 6-month mortality and other non-fatal clinical outcomes such as cardiovascular events (myocardial injury, acute heart failure, myocardial infarction, cardiogenic shock), pneumonia, sepsis, and acute renal injury.

show abstract

Prognostic Significance of Chest Imaging by LUS and CT in COVID-19 Inpatients: The ECOVID Multicenter Study

Cited by 29 publications

References 23 publications

Is Lung Ultrasound Helpful in COVID-19 Neonates?—A Systematic Review

Is Lung Ultrasound Helpful in COVID-19 Neonates?—A Systematic Review

Lung Ultrasound in Children with Cystic Fibrosis in Comparison with Chest Computed Tomography: A Feasibility Study

Usefulness of C2HEST Score in Predicting Clinical Outcomes of COVID-19 in Heart Failure and Non-Heart-Failure Cohorts

Contact Info

Product

Resources

About