Prognostic significance of nuclear DNA analysis by flow cytometry in the progression of superficial bladder cancer

Abstract

The authors used nuclear DNA analysis to evaluate 142 patients with bladder tumours in stage Ta, T1. During follow-up, only the T1G2-G3 forms progressed. Tumour stage and DNA Index (DI) > 1.25 were strongly correlated to tumour invasiveness. According to these data, patients with tumours in the T1 stage and Dl>1.25 should undergo closer follow-up.