Prognostic Significance of Visceral Pleural Involvement in Early-Stage Lung Cancer

Lakha, Sameer; Gomez, Jorge; Flores, Raja M.; Wisnivesky, Juan P.

doi:10.1378/chest.14-0204

Cited by 59 publications

(41 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Revision of the TNM staging system has been a major concern when analyzing VPI status. Kawase et al and Lakha et al concluded that >3‐5 cm/VPI(+) tumors should be upgraded. There were also opinions that the presence of VPI was associated with a poorer survival in tumors >5‐7 cm in size .…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of visceral pleural invasion in non‐small cell lung cancer: A propensity score matching study based on the SEER registry

Yang

Sun

Chen

et al. 2017

Journal of Surgical Oncology

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Prognostic value of visceral pleural invasion in non‐small cell lung cancer: A propensity score matching study based on the SEER registry

Yang

Sun

Chen

et al. 2017

Journal of Surgical Oncology

View full text Add to dashboard Cite

show abstract

“…Lakha and associates [28] assessed the association of visceral pleural invasion with lung cancer-specific and overall survival for 16,315 patients with stage I or II NSCLC treated with lobectomy using the Surveillance, Epidemiology, and End Results data. The results of their Cox analysis found that visceral pleural invasion conferred a significant lung cancer-specific survival disadvantage even after controlling for size and several potential confounders.…”

Section: Commentmentioning

confidence: 99%

Prognostic Role of Subtype Classification in Small-Sized Pathologic N0 Invasive Lung Adenocarcinoma

Yoshiya

Mimae

Tsutani

et al. 2016

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…In a study assessing patients in stages I and II, visceral pleural invasion (VPI) was established to be independently associated with reduced lung cancerspecific survival, upon checking the patients for tumor size and other confounders [19]. Kang et al worked with T2 NSCLC patients that had been subject to resection, and determined visceral pleural invasion to be a factor of poor prognosis.…”

Section: Discussionmentioning

confidence: 99%

Survival in Operated Early and Local Advanced-Stage (IA-IIIA) Non-Small Cell Lung Cancer

Taylan

Arınç²,

Misirlioglu³

et al. 2016

J Clin Exp Invest

View full text Add to dashboard Cite

Objective: The early and local advanced stages (IA-IIIA) of non-small cell lung cancer (NSCLC) warrant the curative treatment approach of surgery. However, despite the surgical approach, survival depends on a number of factors. The aim of the study was to examine the factors that affect survival in operated NSCLC patients with these stages.Methods: A cohort of 231 operated patients with IA, IB, IIA, IIB, and IIIA stages of NSCLC were analyzed. The effects of age, sex, comorbidity, performance status, histopathology of the tumor, T stage, N stage, pleural invasion, surgical resection type and postoperative resection margin invasion on the survival of the patients were examined with KaplanMeier and Cox Regression analyses.Results: Advanced age (OR=1.042 for every passing year, CI=1.020-1.064), adenocarcinoma histopathology (OR=1.676 CI=1.178-2.384), N2 invasion (OR=2.389 CI=1.46-4.239), pleural invasion (OR=2.403 CI=1.569-3.678), resection margin invasion (OR=2.401, CI=1.141-5.048) and pneumonectomy as the type of surgical operation (OR=2.313, CI=1.467-3.647) were found to be independent prognostic factors of mortality. Conclusion:Follow-up of the NSCLC cases with advanced age, an adenocarcinoma type, visceral pleural invasion, N2-lymph node invasion, a history of pneumonectomy, and a resection margin invasion should be undertaken more attentively during planning of surgical operation and postoperative period. Sonuç: İleri yaştaki, adenokanser tipine sahip, viseral plevra invazyonu veya N2 tutulumu olan, pnömomonektomi operasyonu geçiren ve cerrahi sınırda tümör pozitifliği görülen opere erken ve lokal ileri evre KHDAK tanılı hastaların perioperatif ve postoperatif dönemdeki takipleri dikkatli planlanmalıdır.Anahtar kelimeler: sağkalım, mortalite, performans skoru, opere edilmiş, küçük hücreli olmayan akciğer kanseri Taylan M, et al. Survival in Operated Non-Small Cell Lung Cancer

show abstract

Prognostic Significance of Visceral Pleural Involvement in Early-Stage Lung Cancer

Cited by 59 publications

References 23 publications

Prognostic value of visceral pleural invasion in non‐small cell lung cancer: A propensity score matching study based on the SEER registry

Prognostic value of visceral pleural invasion in non‐small cell lung cancer: A propensity score matching study based on the SEER registry

Prognostic Role of Subtype Classification in Small-Sized Pathologic N0 Invasive Lung Adenocarcinoma

Survival in Operated Early and Local Advanced-Stage (IA-IIIA) Non-Small Cell Lung Cancer

Contact Info

Product

Resources

About