Prognostic Survival Factors in Elderly Renal Failure Patients Treated with Peritoneal Dialysis: A Nine-Year Retrospective Study

Genestier, Sandrine; Meyer, Nicolás; Chantrel, F.; Alenabi, Farideh; Brignon, P.; Maaz, Mehadji; Muller, Sandrine; Faller, B

doi:10.3747/pdi.2009.00043

Cited by 34 publications

(42 citation statements)

References 18 publications

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“…Depressive symptoms were present in 24%-55% of patients in the studies that applied a systematic assessment (20,23,27,35), whereas the prevalence of the International Statistical Classification of Diseases diagnosis depression ranged from 4% to 28% (23,29,39,41). Prevalence of cognitive impairment ranged from 6% to 13% in general (25,26,29,31,40) and was 41% in the very old (18). No studies assessed the relation between falls or social environment and poor outcome in the incident dialysis population.…”

Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

“…Most studies focused on one or two geriatric domains only, whereas two studies assessed multiple impairments (Table 1) (29,31). The domain most frequently assessed was performance status, which was described in 12 of the 27 included studies, followed by depression (seven of 27), nutrition (five of 27), and cognition (five of 27).…”

Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

“…Of the remaining publications, 13,083 were excluded for reasons listed in Figure 1; 106 potentially relevant articles were subsequently screened as full text. Ultimately, 27 full-text publications were considered relevant to our search ( Eight studies focused on hemodialysis (27,28,31,33,(35)(36)(37)(38), and three studies focused on peritoneal dialysis only (24,29,43). Fifteen studies performed the screening for impairments at dialysis initiation, and 12 studies performed the screening for impairments within 3 months after initiation.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…The sample size ranged from 40 to 272,024 patients, and the mean age ranged from 53 to 82 years old. Seven studies focused exclusively on elderly patients (mean age ranging from 67 to 82 years old) (18,25,26,29,33,34,42), and one study performed a subgroup analysis of elderly patients (31).…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Table 2 shows the prevalence of the various impairments and lists the various tests and cutoff values used. Performance status was assessed with the Karnofsky Index, the World Health Organization scale, or a national performance scale (Supplemental Table 4), and two studies focused specifically on aspects of ADLs, of which one study used a systematic ADL screening test (29). Severely impaired performance status ranged from 13% to 33%.…”

Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

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The Relevance of Geriatric Impairments in Patients Starting Dialysis: A Systematic Review

Loon

Wouters²,

Boereboom

et al. 2016

CJASN

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Background and objectives With aging of the general population, patients who enter dialysis therapy will more frequently have geriatric impairments and a considerable comorbidity burden. The most vulnerable among these patients might benefit from conservative therapy. Whether assessment of geriatric impairments would contribute to the decision-making process of dialysis initiation is unknown.Design, setting, participants, & measurements A systematic Medline and Embase search was performed on December 1, 2015 to identify studies assessing the association between risk of mortality or hospitalization and one or more geriatric impairments at the start of dialysis therapy, including impairment of cognitive function, mood, performance status or (instrumental) activities of daily living, mobility (including falls), social environment, or nutritional status.Results Twenty-seven studies were identified that assessed one or more geriatric impairments with respect to prognosis. The quality of most studies was moderate. Only seven studies carried out an analysis of elderly patients ($70 years old). Malnutrition and frailty were systematically assessed, and their relation with mortality was clear. In addition, cognitive impairment and functional outcomes at the initiation of dialysis were related to an increased mortality in most studies. However, not all studies applied systematic assessment tools, thereby potentially missing relevant impairment. None of the studies applied a geriatric assessment across multiple domains.Conclusions Geriatric impairment across multiple domains at dialysis initiation is related to poor outcome. However, information in the elderly is sparse, and a systematic approach of multiple domains with respect to poor outcome has not been performed. Because a geriatric assessment has proved useful in predicting outcome in other medical fields, its potential role in the ESRD population should be the subject of future research.

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Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Section: Assessment and Prevalence Of Geriatric Impairmentsmentioning

confidence: 99%

See 3 more Smart Citations

The Relevance of Geriatric Impairments in Patients Starting Dialysis: A Systematic Review

Loon

Wouters²,

Boereboom

et al. 2016

CJASN

View full text Add to dashboard Cite

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Frailty in Older Dialysis Patients

Ilie

Nastasa

Musso-Enz

et al. 2020

Frailty and Kidney Disease

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Hemodialysis-related upper cervical extradural amyloidoma presenting with intractable radiculopathy

et al. 2011

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Introduction Destructive spondyloarthropathy may occur in long-term hemodialysis patients, but focal amyloid deposits in the spine are rare. We present a case of upper cervical extradural amyloidoma with a history of long-term hemodialysis presenting with progressive and intractable radiculopathy. Clinical presentation We describe a 51-year-old female with a long-term history of hemodialysis treatment. She suffered progressive and intolerable right occipital headache. Neurological examination revealed right C2 radiculopathy. Magnetic resonance imaging (MRI) of the cervical spine showed a solid focal extradural mass lesion at the C2 level. She underwent subtotal resection of the extradural mass lesion and decompression of the right C2 nerve root by a posterior approach. Histological examination revealed amyloid deposits. The occipital headache immediately disappeared after surgery. Follow-up MRI 10 months after surgery demonstrated no recurrence of the extradural amyloidoma. Conclusion Development of an upper cervical extradural amyloidoma after long-term hemodialysis is extremely rare. Prompt evaluation of long-term hemodialysis patients suffering from progressive cervical pain should be recommended, and treatment is required if there are signs or symptoms of compression of a nerve root or the spinal cord.

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Prognostic Survival Factors in Elderly Renal Failure Patients Treated with Peritoneal Dialysis: A Nine-Year Retrospective Study

Abstract: Any patient considered for peritoneal dialysis should be evaluated by a multidisciplinary team in collaboration with geriatric specialists for both the overall medical situation and the social and family environment.

Cited by 34 publications

References 18 publications

The Relevance of Geriatric Impairments in Patients Starting Dialysis: A Systematic Review

The Relevance of Geriatric Impairments in Patients Starting Dialysis: A Systematic Review

Frailty in Older Dialysis Patients

Hemodialysis-related upper cervical extradural amyloidoma presenting with intractable radiculopathy

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