Prognostic value of acute kidney injury in patients with community-acquired pneumonia

Serov, V. A.; Shutov, A. M.; Kuzovenkova, Marina; Ivanova, Ya V; Серова, Д. В.

doi:10.17116/terarkh20168869-13

Cited by 1 publication

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References 21 publications

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“…Community-acquired pneumonia (CAP) is the predominant cause of childhood morbidity and mortality in the world, causing nearly 1.2 million deaths annually among children aged <5 years 6 . CAP caused by different pathogens usually affects extrapulmonary organs, as a number of studies have reported that acute kidney injury in adults with CAP was associated with higher mortality and the patient was more likely to require mechanical ventilation [7][8][9] , and similar studies also have been found in children with CAP 10,11 . Moreover, myocardial injury caused by CAP has been widely investigated 12,13 .…”

Section: Introductionmentioning

confidence: 93%

Severe liver injury affects the outcomes and length of hospital stay in children with community-acquired pneumonia

Zhang¹,

Zhao²

2022

Afr H. Sci.

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Background: The present study was undertaken to evaluate the association between liver injury and clinical parameters, outcomes and length of stay (LOS) in hospital in children with community-acquired pneumonia (CAP). Methods: Clinical data and laboratory indicators of 2,573 children with CAP were analyzed. The association between liver injury and clinical parameters, outcomes and LOS was then analyzed. Results: Higher liver injury class was associated with higher incidence of severe CAP, comorbidities, hypoxia, requirement for mechanical ventilation, 30-day mortality and intensive care unit admission, and higher indicators of inflammation (C-reactive protein, procalcitonin and white blood cell count), longer LOS, faster respiratory rate and pulse rate, and lower age, serum albumin levels, monocyte and lymphocyte counts. Severe liver injury was identified as an independent factor for 30-day mortality and prolonged LOS in children with CAP. Higher liver injury class was associated with a lower cumulative survival rate (p=0.0004), and log-rank test for trend was used to demonstrate the association of each injury class with 30-day mortality (p=0.0002). Conclusions: Several parameters were associated with liver injury in children with CAP. Severe liver injury was found to be an independent factor for 30-day mortality and LOS in children with CAP. Keywords: Community-acquired pneumonia; liver injury; children; mortality; hospital length of stay.

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Section: Introductionmentioning

confidence: 93%

Severe liver injury affects the outcomes and length of hospital stay in children with community-acquired pneumonia

Zhang¹,

Zhao²

2022

Afr H. Sci.

View full text Add to dashboard Cite

show abstract

Prognostic value of acute kidney injury in patients with community-acquired pneumonia

Abstract: AKI complicates CAP in 28.3% of cases and increases mortality in patients with CAP. The predictors of AKI in CAP patients are old age, hemodynamic disorders, diabetes mellitus, and prior urinary tract diseases.

Cited by 1 publication

References 21 publications

Severe liver injury affects the outcomes and length of hospital stay in children with community-acquired pneumonia

Severe liver injury affects the outcomes and length of hospital stay in children with community-acquired pneumonia

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