Prognostic value of adenosine single-photon emission computed tomographic thallium imaging in medically treated patients with angiographic evidence of coronary artery disease

Kamal, Abdalla Mostafa; Fattah, Alia Abdel; Pancholy, Samir; Aksut, Seidy; Cave, Virginia; Heo, Jaekyeong; Iskandrian, Abdulmassih S.

doi:10.1007/bf02940339

Cited by 37 publications

(5 citation statements)

References 26 publications

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“…Second, MPI has been reported to be limited in its ability in women, as it has been found to produce false-positive results due to breast attenuation and small left ventricular chamber size [40]. Despite this limitation, many studies have reported women with an abnormal MPI finding to be at significantly increased risk for cardiac events [41][42][43][44][45][46][47]. Berman et al [41] found that the greater the abnormality of the MPI is, the greater is the risk of cardiac death in men and women, with diabetic women appearing to be at greater risk of cardiac death than diabetic men for any MPI result.…”

Section: Discussionmentioning

confidence: 99%

High-sensitivity C-reactive protein and silent myocardial ischemia in Chinese with type 2 diabetes mellitus

Hsieh

Tien

Chang³

et al. 2008

Metabolism

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Section: Discussionmentioning

confidence: 99%

High-sensitivity C-reactive protein and silent myocardial ischemia in Chinese with type 2 diabetes mellitus

Hsieh

Tien

Chang³

et al. 2008

Metabolism

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“…In patients with known CAD, the severity of perfusion defects is associated with increased cardiac risk [14,15]. Normal MPI results, even in patients with multivessel CAD, portend a very favorable prognosis, with a low risk of cardiac events [16,17].…”

Section: Value Of Physiologic Imagingmentioning

confidence: 99%

Integrated imaging of cardiac anatomy, physiology, and viability

Arrighi

2009

Curr Cardiol Rep

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Technologic developments in imaging will have a significant impact on cardiac imaging over the next decade. These advances will permit more detailed assessment of cardiac anatomy, complex assessment of cardiac physiology, and integration of anatomic and physiologic data. The distinction between anatomic and physiologic imaging is important. For assessing patients with known or suspected coronary artery disease, physiologic and anatomic imaging data are complementary. The strength of anatomic imaging rests in its ability to detect the presence of disease, whereas physiologic imaging techniques assess the impact of disease, such as whether a coronary atherosclerotic lesion limits myocardial blood flow. Research indicates that physiologic data are more prognostically important than anatomic data, but both may be important in patient management decisions. Integrated cardiac imaging is an evolving field, with many potential indications. These include assessment of coronary stenosis, myocardial viability, anatomic and physiologic characterization of atherosclerotic plaque, and advanced molecular imaging.

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“…Kamal et al [30] evaluated 177 patients with CAD with adenosine Tl SPECT. Actuarial life-table analysis showed that patients with a perfusion defect size less than 15% had better event-free survival than patients with defects of 15% or greater.…”

Section: Patients With Known or Suspected Coronary Diseasementioning

confidence: 99%

Pharmacologic radionuclide myocardial perfusion imaging

Navare¹,

Kapetanopoulos²,

Heller

2003

Curr Cardiol Rep

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Pharmacologic stress testing with myocardial perfusion imaging has enabled patients who cannot complete adequate exercise to undergo diagnostic and prognostic evaluation for coronary artery disease. Pharmacologic stress agents belong to two groups: vasodilators (such as adenosine and dipyridamole), and inotropes (such as dobutamine). All have similar sensitivity (89%-91%) and specificity (78%-86%) for the diagnosis of coronary disease. For risk stratification, the risk of future cardiac events is related to the extent and severity of perfusion abnormalities. Pharmacologic stress testing permits risk stratification as early as 1 to 4 days following an acute myocardial infarction, and is superior to exercise stress testing in this regard. Similarly, it identifies patients at high risk for perioperative cardiac events prior to noncardiac surgery. This review summarizes the current evidence available regarding the diagnostic and prognostic use of pharmacologic stress testing.

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Prognostic value of adenosine single-photon emission computed tomographic thallium imaging in medically treated patients with angiographic evidence of coronary artery disease

Abstract: Thus adenosine single-photo emission computed tomographic thallium imaging provides important prognostic data in medically treated patients with CAD. The extent of thallium abnormality is the most important predictor of events.

Cited by 37 publications

References 26 publications

High-sensitivity C-reactive protein and silent myocardial ischemia in Chinese with type 2 diabetes mellitus

High-sensitivity C-reactive protein and silent myocardial ischemia in Chinese with type 2 diabetes mellitus

Integrated imaging of cardiac anatomy, physiology, and viability

Pharmacologic radionuclide myocardial perfusion imaging

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