Prognostic Value of Cardiac Tests in Potential Kidney Transplant Recipients

Wang, Louis W.; Masson, Philip; Turner, Robin; Lord, Sue; Baines, Laura; Craig, Jonathan C.; Webster, Angela C

doi:10.1097/tp.0000000000000611

Cited by 73 publications

(82 citation statements)

References 59 publications

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“…DSE may induce atrial fibrillation. Nonetheless, DSE may be preferred in transplant candidates who have a low blood pressure or reactive airways disease [5] . A widely discussed topic in the current literature is the comparison of DSE to MPS in kidney transplant candidates.…”

Section: Dobutamine Stress Echocardiographymentioning

confidence: 99%

“…An average dose of 15 milliSievert corresponds to approximately 750 chest Xrays [36] . Nonetheless, based on a recent systematic review [5] , MPS does have predictive value for major adverse cardiac events (based on 19 studies) but not all cause mortality (based on 11 studies). "Fixed" perfusion defects, for which intervention is not usually pursued, also have prognostic value [5] .…”

Section: Myocardial Perfusion Scintigraphymentioning

confidence: 99%

“…Nonetheless, based on a recent systematic review [5] , MPS does have predictive value for major adverse cardiac events (based on 19 studies) but not all cause mortality (based on 11 studies). "Fixed" perfusion defects, for which intervention is not usually pursued, also have prognostic value [5] . MPS may reveal no discernible distinct territory with ischemia, but global ischemia may still be present as a result of balancing large vessels being occluded or as a result of diffuse microvascular occlusion from conditions like diabetes.…”

Section: Myocardial Perfusion Scintigraphymentioning

confidence: 99%

“…Various forms of MPS are usually available to transplant programs. MPS is the preferred test if blood pressure is uncontrolled or a cardiac arrhythmia is present [5] . Dipyradimole is the pharmacologic agent typically used to increase endogenous adenosine levels, which in turn results in vasodilation and stress to cardiac muscle as a result of challenging the flow reserve.…”

Section: Myocardial Perfusion Scintigraphymentioning

confidence: 99%

“…Particular emphasis will be placed on practical considerations in pretransplant screening rather than on statistical comparisons among screening tests or consequent management either before or after the transplant. Our goal is to supplement such information already contained in excellent consensus statements [2] and recent reviews [5] , among others on these topics.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Screening for cardiovascular disease before kidney transplantation

Palepu

Prasad

2015

WJT

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Pre-kidney transplant cardiac screening has garnered particular attention from guideline committees as an approach to improving post-transplant success. Screening serves two major purposes: To more accurately inform transplant candidates of their risk for a cardiac event before and after the transplant, thereby informing decisions about proceeding with transplantation, and to guide pre-transplant management so that posttransplant success can be maximized. Transplant candidates on dialysis are more likely to be screened for coronary artery disease than those not being considered for transplantation. Thorough history and physical examination taking, resting electrocardiography and echocardiography, exercise stress testing, myocardial perfusion scintigraphy, dobutamine stress echocardiography, cardiac computed tomography, cardiac biomarker measurement, and cardiac magnetic resonance imaging all play contributory roles towards screening for cardiovascular disease before kidney transplantation. In this review, the importance of each of these screening procedures for both coronary artery disease and other forms of cardiac disease are discussed.

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Section: Dobutamine Stress Echocardiographymentioning

confidence: 99%