Prognostic value of left atrial volume index in patents with first acute myocardial infarction

Abstract

AimsWe evaluated the usefulness of left atrial volume index (LAVI) and the degree of changes in LAVI (delta LAVI) during hospitalization for the prediction of prognosis after acute myocardial infarction (AMI). Methods and resultsWe investigated 205 consecutive patients with first AMI. They underwent echocardiography on admission as well as at discharge. Delta LAVI was calculated by subtracting the value on admission from that at discharge. The primary endpoints were major cardiac events (MACE): cardiac death due to heart failure and heart failure hospitalization. During a mean follow-up of 26 months, MACE occurred in 29 patients. Patients were divided into two groups according to the optimal cut-off values of LAVI (32.0 mL/m 2 ) at discharge and delta LAVI (2.5 mL/m 2 ) derived from receiver operating characteristic curves, respectively; Group I: LAVI ≤ 32.0 mL/m 2 , Group II: LAVI . 32.0 mL/m 2 and Group A: delta LAVI ≤ 2.5 mL/m 2 , Group B: delta LAVI . 2.5 mL/m 2 . In comparisons of two groups, respectively, the incidence of MACE between the groups showed significant differences [Group I (3.8%) vs. Group II (32.0%): P , 0.001, log-rank, Group A (7.4%) vs. Group B (20.0%): P ¼ 0.0079, log-rank]. In multivariate analysis, LAVI at discharge [risk ratio (RR): 1.077, 95% CI: 1.035-1.124, P ¼ 0.0002] and delta LAVI (RR: 1.056, 95% CI: 1.012 -1.108, P ¼ 0.0109) were significant. LAVI . 32.0 mL/m 2 at discharge (sensitivity: 93%, specificity: 69%) and delta LAVI . 2.5 mL/m 2 (sensitivity: 79%, specificity: 50%) were predictors of MACE. ConclusionLAVI at discharge and delta LAVI would be useful predictors for MACE after first AMI.--

Mitral stenozda sol atrial volüm indexi ve Sağ ventrikül dilatasyonunun atrial fibrilasyon için prediktif değeri

“…LAVI is as well as an important marker in the development of atrial fibrillation and seems to be an important parameter in predicting atrial fibrillation. The importance of LAVI, it has been used in atrial fibrillation, for monitoring of the success of electrical cardioversion and the formation of and recurrence, the results of mitral balloon valvuloplasty, and prognosis of acute myocardial infarction and development of major cardiac event, and to predict AF recurrences after radiofrequency ablation and it has been shown that, increased LAVI values were associated with poor prognosis 6,18,19,20 . However, in these studies, the cut off value of LAVI for AF has not been reported.…”

“…The duration of mitral stenosis is preparing ground for the formation of atrial fibrillation. Left atrial pressure increase caused by long-term mechanical obstruction is preparing ground for the development of atrial fibrillation 10,11,20 . In parallel to these findings in our study, we determined that the average age of patients with AF was more.…”

Predictive Value of Echocardiography in Post Myocardial Infarction Setting. Part 2

“…В противоположность этому объём левого предсердия (ЛП) менее зависим от острых гемодинамических изменений и отражает подострую или хроническую диастолическую дис-функцию. Прогностическое значение размера и объ-ёма ЛП после ИМ изучалось в нескольких исследова-ниях [28][29][30].…”

Prognostic value of new left atrial volume index severity partition cutoffs after cardiac rehabilitation program in patients undergoing cardiac surgery

“…LA also reflects LV filling pressure and is capable of remodeling (enlarging) in response to its elevation [1, 2]. Although there is a growing body of evidence demonstrating that LA enlargement is an independent marker of adverse outcomes both in primary [3–7] and secondary [8–11] cardiovascular prevention, to date, there are no published data assessing long-term outcome in patients undergoing valve and coronary artery by-pass graft (CABG) surgery.…”