Prognostic value of metabolic syndrome for the development of cardiovascular disease in a cohort of premenopausal women with systemic lupus erythematosus

García-Villegas, Elsy Aidé; Lerman-Garber, Israel; Flores‐Suárez, Luis Felipe; Aguilar-Salinas, Carlos A.; González, Horacio Márquez; Villa-Romero, Antonio Rafael

doi:10.1016/j.medcli.2014.06.018

Cited by 10 publications

(20 citation statements)

References 24 publications

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“…After reading titles or abstracts, 1846 records were removed because of duplication, irrelevance to SLE or our topic or review. Finally, 47 eligible studies which met the inclusion criteria were identified and included in this meta‐analysis . The detailed selection process is shown in Figure .…”

Section: Resultsmentioning

confidence: 99%

Prevalence and risk of metabolic syndrome in patients with systemic lupus erythematosus: A meta‐analysis

Sun

Qin²,

Zhang

et al. 2017

Int J of Rheum Dis

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Section: Resultsmentioning

confidence: 99%

Prevalence and risk of metabolic syndrome in patients with systemic lupus erythematosus: A meta‐analysis

Sun

Qin²,

Zhang

et al. 2017

Int J of Rheum Dis

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“…The prevalence of MetS in SLE patients in different studies varied from 16.3% to 45.2%, and the relative risk of cardiovascular disorders in a subgroup of SLE patients that fit into the MetS criteria in comparison with patients without MetS was 2.48. 3,8,9 MetS is related to the inflammatory response, and proinflammatory cytokines such as interleukin (IL)-6 and tumor necrosis factor (TNF)-a facilitate insulin resistance. Patients with MetS present high levels of Creactive protein (CRP), IL-1b, IL-1RA, P-selectin, intercellular adhesion molecule and leptin.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, assessment of the prevalence of MetS and its components is particularly important in patients with SLE. The prevalence of MetS in SLE patients in different studies varied from 16.3% to 45.2%, and the relative risk of cardiovascular disorders in a subgroup of SLE patients that fit into the MetS criteria in comparison with patients without MetS was 2.48 …”

Section: Introductionmentioning

confidence: 99%

Metabolic syndrome in patients with systemic lupus erythematosus: Association with disease activity, disease damage and age

et al. 2018

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“…The prevalence of the different CVD risk factors in SLE patients ranges between 20–50% for hypertension, 3–9% for diabetes mellitus, 9–15% for dyslipidemia, 15–38% for smoking, and 16–22% for metabolic syndrome (compared to 5–6% in the general population) . Despite the increased prevalence of CVD risk factors in SLE patients, many lupus patients are not aware of their increased risk of CVD, and they do not receive routine screening and counseling for CVD risk factors .…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Disease Prevention Counseling Program for Systemic Lupus Erythematosus Patients

Yelnik

Richey

Haiduc

et al. 2017

Arthritis Care & Research

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Objective To determine if a cardiovascular disease prevention (CVD) counseling program for lupus patients decreases the prevalence of CVD risk factors. Methods The assessment phase of three-year CVD prevention counseling program included the evaluation of CVD risk factors, diet, exercise habits, and medications. The education phase included discussion of the above risk factors as well as CVD and thrombosis prevention strategies. Patients were prospectively followed every 3–6 months for risk assessment and continued education by a nurse practitioner and a medical doctor. Results Between March 2009 and December 2014, 121 patients were included. At baseline, abnormal blood pressure, blood glucose, cholesterol profile, and body mass index were found in 50 (41%), 7 (6%), 82 (68%), and 77 (64%) of patients, respectively. During the three-year follow-up, among those with abnormal baseline values: a) prevalence of abnormal blood pressure significantly decreased (OR: 0.94, 95% CI: 0.92–0.96, p<0.0001) with significant mean systolic blood pressure improvement (−6.12 ± 2.16 mmHg, p<0.05); b) prevalence of abnormal cholesterol profile significantly decreased (OR: 0.90; 95% CI: 0.92–0.96) with significant improvements in mean high-density lipoprotein (+5.4 ± 0.36 mg/dl, p<0.0001) and mean triglyceride levels (−12.6 ± 0.81 mg/dl, p<0.05); and c) no significant change in blood glucose and body mass index were observed. At baseline, 100 (83%) and 95 (79%) patients had poor diet and physical activity; during the follow-up, both significantly improved in the entire population. Conclusion Our data suggest that a CVD prevention counseling program decreases the prevalence of some CVD risk factors in lupus patients.

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Prognostic value of metabolic syndrome for the development of cardiovascular disease in a cohort of premenopausal women with systemic lupus erythematosus

Cited by 10 publications

References 24 publications

Prevalence and risk of metabolic syndrome in patients with systemic lupus erythematosus: A meta‐analysis

Prevalence and risk of metabolic syndrome in patients with systemic lupus erythematosus: A meta‐analysis

Metabolic syndrome in patients with systemic lupus erythematosus: Association with disease activity, disease damage and age

Cardiovascular Disease Prevention Counseling Program for Systemic Lupus Erythematosus Patients

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