Prognostic value of Microvolt T wave alternans in patients with left ventricular systolic dysfunction: A meta-analysis

T-Wave Analysis on the 24 h Holter ECG Monitoring as a Predictive Assessment of Major Adverse Cardiovascular Events in Patients with Myocardial Infarction: A Literature Review and Future Perspectives

“…The studies conducted by Schuster et al, Verrier et al and Maytin et al investigated the predictive value of T-wave aspects, particularly TWA, in patients with stable angina or coronary artery disease [ 154 , 155 ]. In Schuster et al’s study, 139 patients underwent both TWA testing and coronary angiography to assess the complexity and severity of coronary artery disease using the Syntax score.…”

“…In Verrier et al’s study, 186 patients with stable coronary artery disease were followed for 25 months after undergoing TWA testing during exercise treadmill testing and coronary angiography to assess the presence and severity of coronary artery disease. During follow-up, 23 MACE events occurred, and TWA was found to be a significant predictor of MACE, independent of angiographic and clinical variables [ 154 ]. Similarly, in Maytin et al’s study, 605 patients with stable coronary artery disease were followed for a median of 3.5 years after undergoing TWA testing during exercise treadmill testing and coronary angiography to assess the severity of coronary artery disease using the Gensini score.…”

“…These studies suggest that T-wave aspects, particularly TWA, may be useful in predicting MACE in patients with stable or unstable coronary artery disease, independent of the severity of coronary artery disease assessed by coronary angiography or other clinical variables. However, more research is needed to determine the optimal use of T-wave aspects in risk stratification and clinical decision-making [ 154 , 155 ].…”

“…In summary, these studies indicate that T-wave parameters, particularly TWA, may be valuable in predicting MACE in patients with stable or unstable coronary artery disease, regardless of coronary angiography results. Nevertheless, further research is required to establish the optimal application of T-wave parameters in clinical decision-making and risk stratification [ 68 , 154 , 155 ].…”

“…The [154,155]. In Schuster et al's study, 139 patients underwent both TWA testing and coronary angiography to assess the complexity and severity of coronary artery disease using the Syntax score.…”