Prognostic value of serial six-minute walk tests using tele-accelerometry in patients with chronic heart failure: A pre-specified sub-study of the TIM-HF-Trial

Prescher, Sandra; Schoebel, Christoph; Koehler, Kerstin; Deckwart, Oliver; Wellge, Brunhilde; Honold, Marcus; Hartmann, Oliver; Winkler, Sebastian; Koehler, Friedrich

doi:10.1177/2047487316671438

Cited by 19 publications

(18 citation statements)

References 15 publications

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“…The 6MWD is a widely used tool to assess functional capacity in a wide range of populations, including CVD patients. Several studies demonstrated its ability to predict outcome including heart failure, 7,8 coronary artery disease, 9 and those undergoing cardiac surgery. 6,10 1.00 It has also been suggested that the prognostic utility of 6MWD is comparable to that of cardiopulmonary exercise testing.…”

Section: Discussionmentioning

confidence: 99%

Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Kamiya

Hamazaki

Matsue

et al. 2017

Eur J Prev Cardiolog

104

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Background Although gait speed and six-minute walk distance are used to assess functional capacity in older patients with cardiovascular disease, their prognostic capabilities have not been directly compared. Methods The study population was identified from the Kitasato University Cardiac Rehabilitation Database and consisted of 1474 patients ≥60 years old with a mean age of 72.2 ± 7.1 years that underwent evaluation of both usual gait speed and six-minute walk distance in routine geriatric assessment between 1 June 2008-30 September 2015. Both gait speed and six-minute walk distance were determined on the same day at hospital discharge. Results Mean gait speed and six-minute walk distance in the whole population were 1.04 m/s and 381 m, respectively, and were strongly positively correlated ( r = 0.80, p < 0.001). A total of 180 deaths occurred during a follow-up of 2.3 ± 1.9 years. After adjusting for confounding factors, both gait speed (adjusted hazard ratio per 0.1 m/s increase: 0.87, 95% confidence interval: 0.81-0.93, p < 0.001) and six-minute walk distance (adjusted hazard ratio per 10-metre increase: 0.96, 95% confidence interval: 0.94-0.97, p < 0.001) were independent predictors of all-cause mortality. There was no significant difference in prognostic capability between gait speed and six-minute walk distance (c-index: 0.64 (95% confidence interval: 0.60-0.69) and 0.66 (95% confidence interval: 0.61-0.70), respectively, p = 0.357). Conclusions Gait speed and six-minute walk distance showed similar prognostic predictive ability for all-cause mortality in older cardiovascular disease patients, indicating the potential utility of gait speed as a simple risk stratification tool in older cardiovascular disease patients.

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Section: Discussionmentioning

confidence: 99%

Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Kamiya

Hamazaki

Matsue

et al. 2017

Eur J Prev Cardiolog

104

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“…Furthermore, tele-6MWD showed a high predictive role with respect to readmission or all-cause mortality in patients with heart failure, and the values were comparable to the prognostic impact of the conventional 6MWD. 9 Overall, these findings suggesting that 6MWD is a strong indicator of poor prognosis in patients with heart failure.…”

mentioning

confidence: 87%

Prognostic value of six-minute walk distance in patients with heart failure: A meta-analysis

Fan

Zhang

2018

Eur J Prev Cardiolog

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“…The experiment was a test for the motor function status of patients with moderate to severe HF ( 21 ), which examined the motion state of patients from both the Research and Control Groups before the treatment, 1 day after the treatment, and 7 days after the treatment. The test site was an unimpeded corridor with one chair placed every 15 meters for the patients to rest halfway.…”

Section: Methodsmentioning

confidence: 99%

Comparison of clinical efficacy of metoprolol combinedwith irbesartan and hydrochlorothiazide and non-invasive ventilator in the emergency treatment of patients with severe heart failure

et al. 2018

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Clinical efficacy of metoprolol combined with irbesartan and hydrochlorothiazide and non-invasive ventilator in the emergency treatment of patients with severe heart failure (HF) was investigated. A retrospective analysis of the medical records of 124 patients with severe HF admitted to Binzhou Medical University Hospital from May 2012 to August 2016 was performed. Among them, 78 patients who were treated with metoprolol combined with irbesartan and hydrochlorothiazide and non-invasive ventilator for emergency treatment were enrolled into the Research Group, while the Control Group consisted of 46 patients treated with routine medical treatment. Echocardiographic parameters, 6-minute walking test results, the efficacy of the emergency treatment, cardiac function grading, left ventricular ejection fraction (LVEF) and brain natriuretic peptide (BNP) levels were compared between the two groups. After the emergency treatment, the echocardiographic indexes of both groups increased to different extents (P<0.05). Compared with the results before, patients of both groups walked longer within six minutes after the emergency treatment (P<0.05). After the emergency treatment, the BNP expression levels in the two groups decreased to different degrees (P<0.05). After a 7-day emergency treatment, the efficiency rate of treatment of the Research Group was higher than that of the Control Group (P<0.05). The method is helpful for the recovery of respiratory function, for relieving symptoms in short time, improving cardiac function and promising high safety, using metoprolol and irbesartan and hydrochlorothiazide combined with non-invasive ventilator had satisfactory clinical efficacy in the emergency treatment of patients with severe heart failure and is thus worthy of clinical promotion.

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Prognostic value of serial six-minute walk tests using tele-accelerometry in patients with chronic heart failure: A pre-specified sub-study of the TIM-HF-Trial

Cited by 19 publications

References 15 publications

Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Prognostic value of six-minute walk distance in patients with heart failure: A meta-analysis

Comparison of clinical efficacy of metoprolol combinedwith irbesartan and hydrochlorothiazide and non-invasive ventilator in the emergency treatment of patients with severe heart failure

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