Prognostic value of serum pregnancy-associated plasma protein A level at the initial ED presentation in elderly patients with CAP

Golcuk, Yalcin; Golcuk, Burcu; Bilge, Adnan; Korkmaz, Ayhan; Irik, Mehmet; Hayran, Mustafa; Özdemir, Alper Tunga; Kurtulmus, Yusuf

doi:10.1016/j.ajem.2015.05.047

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…Hospital-acquired pneumonia (HAP) was defi ned as pneumonia that occurs at ≥ 48 hours after admission and was absent during admission. Healthcare-associated pneumonia (HCAP) was defi ned for patients who (1) had undergone hospitalization (≥ 2 days), home infusion therapy (including antibiotics), and/or home wound care in the preceding 90 days; (2) had undergone chronic dialysis within the last 30 days; (3) were residents of nursing homes or extended care facilities; and/or (4) had family members with multidrug-resistant pathogens (10).…”

Section: Defi Nitions and Clinical Scoring Toolsmentioning

confidence: 99%

Comparison of inflammation markers with prediction scores in patients with community-acquired pneumonia

Acar¹,

Gökçen²,

Demir³

et al. 2021

BLL

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OBJECTIVE: The lymphocyte-to-C-reactive protein ratio (LCRP) and Systemic Immune-Infl ammation Index (SII) can successfully predict 28-day mortality rates with community-acquired pneumonia METHODS: This prospective study was conducted in 2018. Hospitalized patients underwent follow-up evaluations 28 days after admission. RESULTS: A total of 345 patients with CAP were enrolled in this study. All-cause mortality at the 28th day of follow-up was 13.6 %. There were statistically signifi cant results between the 2 groups (survivors and nonsurvivors), in terms of the LCRP, SII, PSI, and CURB-65 values. Moreover, the optimal LCRP cutoff for predicting 28-day mortality was determined to be 4, with 89 % sensitivity, 73 % specifi city. Based on the average SII>3551for predicting 28-day mortality, the sensitivity, specifi city was 63.8 %, 68.1 % respectively. When the value of the cutoff PSI was ≥130 points, the sensitivity, specifi city was 68 %, 65 %, respectively. Based on 3 points and above as the cutoff value of the CURB-65 score, the sensitivity, specifi city was 80 %, 68 %, respectively. ROC curve analysis revealed that the areas of LCRP, SII, PSI, and CURB-65 under the AUC in terms of 28day mortality were 0,820,0,737,681, and 0,773, respectively, CONCLUSIONS: LCRP and SII level are valuable for predicting the mortality rate among patients with CAP at ED admission

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Section: Defi Nitions and Clinical Scoring Toolsmentioning

confidence: 99%