Prognostischer Einfluss der Infiltrationstiefe von Mundhöhlen- und Oropharynxkarzinomen

Wenzel, Stefan; Sagowski, C.; Kehrl, W.; Metternich, F. U.

doi:10.1007/s00106-003-0962-3

Cited by 7 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bei Vorliegen von Lymphknotenmetastasen verlieren Parameter des Primärtu-mors an prognostischer Aussagekraft [25,30,45,48], sodass der N-Klassifizierung eine zusätzliche differenzierende Bedeutung zukommt. Das entscheidende Kriterium Lymphknotenmetastasierung lässt sich mittels der histologischen Unterteilung in intra-und extranodales Tumorwachstum weiter aufgliedern.…”

Section: Schlussfolgerungen Und Ausblickunclassified

Plattenepithelkarzinome des oberen Aerodigestivtraktes

Wenzel

Koch

2004

HNO

Self Cite

View full text Add to dashboard Cite

The capsular rupture and subsequent extranodal spread of lymph node metastases is of crucial and well established prognostic value in patients with squamous cell carcinomas of the upper aerodigestive tract. Besides the basic histologic definition of the extranodal spread (i.e. contact of the metastasis with perinodal fatty tissue), there is no agreement on the morphologic extent of transcapsular spread. As a measure of improvement, a histologic evaluation differentiating between seven gradual types of metastatic nodal affection was applied. The histologic scheme considers intranodal growth, infiltration of the capsule, the presence of desmoplasia and especially the rupture of the capsule and the subsequent extranodal spread of the metastasis. As extranodal spread is an easily reproducible and reliably significant prognostic criterion, it should be included in the current TNM classification, e.g., by an addition of the index R+ (lymph node metastasis with capsular rupture) or R- (lymph node metastasis without capsular rupture) to the N category.

show abstract

Section: Schlussfolgerungen Und Ausblickunclassified

Plattenepithelkarzinome des oberen Aerodigestivtraktes

Wenzel

Koch

2004

HNO

Self Cite

View full text Add to dashboard Cite

show abstract

Notwendigkeit der Bluttransfusion bei ausgewählten Operationen im Kopf-Hals-Bereich

Jecker

Melzer

Hitzler

2005

HNO

View full text Add to dashboard Cite

show abstract

Analysis of Survival Rates Following Primary Surgery of 178 Consecutive Patients with Oral Cancer in a Large District General Hospital

Stathopoulos

Smith

2016

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

As almost half of our patients presented with advanced cancer and had discouraging survival rates, we emphasize the need for early recognition of the disease. Advanced disease signifies difficulty in obtaining clear margins which actually indicates a higher recurrence rate. 25 % of our patients died of oral cancer within 5 years of surgery which highlights the poor prognosis that recurrence carries after treatment. Effective educational campaign with purpose to raise oral cancer awareness and earlier referral may result in improvement of survival.

show abstract

Prognostischer Einfluss der Infiltrationstiefe von Mundhöhlen- und Oropharynxkarzinomen

Cited by 7 publications

References 27 publications

Plattenepithelkarzinome des oberen Aerodigestivtraktes

Plattenepithelkarzinome des oberen Aerodigestivtraktes

Notwendigkeit der Bluttransfusion bei ausgewählten Operationen im Kopf-Hals-Bereich

Analysis of Survival Rates Following Primary Surgery of 178 Consecutive Patients with Oral Cancer in a Large District General Hospital

Contact Info

Product

Resources

About