The diffraction characteristics of orthogonal gratings with variable duty cycles and phase modulation depths are analyzed by using a spatial light modulator. The calculation methods of the transmission function, far-field diffraction light field, and diffraction efficiency of orthogonal gratings are deduced in theory. Meanwhile, the influences of the duty cycle and phase modulation depth on the diffraction characteristics of the orthogonal grating are discussed. The simulation and experimental results verify the correctness of the theoretical derivation. This method can be widely used in the fields of an optical vortex array, laser parallel processing, optical computing, optical communication, and optoelectronic hybrid processing.