This scientific work examines the role of political institutions in the formation of the state’s social policy, with a focus on the part that concerns issues of protecting public health. Next, politics on protection of health of population (or health policy) is considered in the prism of global processes. Purpose. The purpose of this work is to study issues of social policy, in particular, its part relating to health care, in the context of global politics and to analyze the role of political institutions in the process of its formation and implementation. Methods. During the research, works devoted to the issues covered in the topic of the work were studied, in particular, the very concept of political institutions and the meaning of social policy were analyzed. A literature review was conducted and results were generated based on methods of generalization and comparative analysis. Main results and conclusions. Based on the materials studied, a conclusion is made about the key role of political institutions in the development and implementation of social policy, which on a global scale influences global health issue. The conclusion is made about the need for a more detailed study of the importance of the involvement of political institutions in the formation of policies to protect public health.