2014
DOI: 10.1016/j.clinbiochem.2013.12.023
|View full text |Cite
|
Sign up to set email alerts
|

Programmed death-1 (PD-1) polymorphisms in Chinese patients with esophageal cancer

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
36
0
4

Year Published

2016
2016
2023
2023

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 39 publications
(40 citation statements)
references
References 38 publications
0
36
0
4
Order By: Relevance
“…The etiology of EGJA is very complicated. Accumulating evidences demonstrated that SNPs in some immune response genes might be associated with risk of cancer [6, 26–28]. In consideration of the vital role of PD-1 in tumor immunology, we chose PD-1 rs10204525 T>C, rs2227982 A>G, rs36084323 T>C and rs7421861 A>G polymorphisms to examine their potential roles in EGJA.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…The etiology of EGJA is very complicated. Accumulating evidences demonstrated that SNPs in some immune response genes might be associated with risk of cancer [6, 26–28]. In consideration of the vital role of PD-1 in tumor immunology, we chose PD-1 rs10204525 T>C, rs2227982 A>G, rs36084323 T>C and rs7421861 A>G polymorphisms to examine their potential roles in EGJA.…”
Section: Discussionmentioning
confidence: 99%
“…Some epidemiological studies focused on the effect of PD-1 rs7421861 A>G locus on the development of multiple cancers; however, the results remained inconsistent. Several case-control reported that PD-1 rs7421861 A>G polymorphism was not associated with cancer risk [19, 27, 28, 30]. However, Ge et al .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Esophageal squamous cell carcinoma (ESCC), as the major pathological type, has become a major health threat to Chinese [2]. Despite great advance in the treatment strategies, the clinical outcomes of ESCC patients remained unsatisfactory [2, 3]. According to Siegel's cancer statistics, the 5-year survival rate was 49.3% for localized disease and only 2.8% for metastatic disease [4].…”
Section: Introductionmentioning
confidence: 99%
“…According to Siegel's cancer statistics, the 5-year survival rate was 49.3% for localized disease and only 2.8% for metastatic disease [4]. Among the risk factors involving in the prognosis of ESCC patients, the host immune responses, tumor infiltrating immune cells and cytokines, are of great importance [3, 5-7]. The infiltration of IL-17+ cells plays bipolar roles in tumor immunity: tumor protective immunity or pro-tumor immunity [6, 7].…”
Section: Introductionmentioning
confidence: 99%