The purpose of this article is to analysis the factors affecting the effectiveness of the education system in Ukraine. The article substantiates the need to determine the main criteria and tools for assessing quality for subsequent decision-making at the level of educational institutions, educational management, and added value. Results from DEAP Version 2.1 of technical efficiency contain information on CRS, VRS, and SEa models grouped by 24 regions of Ukraine. A set of control variables determined their impact on the effectiveness of the higher education system in Ukraine. Practical application of Data envelopment analysis (DEA) methods and regression analysis, graphical analysis, made it possible to form an idea of qualitative and quantitative indicators that affect the efficiency of the education system in Ukraine.