Progress in Cell Cycle Research

Abstract

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.Front Cover: A triple exposure fluorescent photomicrograph of a new lung epithelial cell (pneumocyte) in metaphase of mitosis. After fixation in glutaraldehyde this cell was stained for the indirect immunofluorescent localizat ion ofmicrotubules (green) using a monoclonal antibody against alpha-tubulin and an FITC-conjugated secondary antibody. It was then similarly stained for keratin-type intermediate filaments (red) using a rabbit polyclonal antibody and a TRITC-conjugated secondary antibody. Finally the chromosomes (blue) were counter stained with Hoechst 33342. In newts, as in most vertebrate epithelia, the spindle forms within a "cage" of intermediate filaments that sterically impede the migration of other large cellular components into the area formerly occupied by the nucleus. Micrograph courtesy of Conly L. Rieder and Alexey Khodjakov, Wadworth Center, Albany, New York (see related article in this volume.) ISBN 978-1-4613-7451-0 ISBN 978-1-4615-5371-7 (eBook)