Progress in Development of Molecularly Imprinted Polymers as Sorbents for Sample Preparation

Solid-Phase Extraction for Enrichment and Separation of Herbicides

“…The retention on blanks seems to be a good reflection of the relative affinity of monomers to the herbicides, and this interaction must be naturally strong enough to allow the binding enhancement by a MIP. Proper selection of reagents, reaction medium and conditions should take into consideration the complexity of selective sites formation in the polymer structure to obtain a material capable of not only highly selective recognition of target analytes but also having good kinetic parameters (Kloskowski et al, 2009). Kopohpaei et al (2008) proposed a chemometric approach for the optimization of the main factors affecting the material structure and the molecular recognition properties of the MIPs.…”

Electrospun nanofiber sorbents for the pre-concentration of urinary 1-hydroxypyrene

“…It was anticipated that the sorbents would interact well with 1-hydroxypyrene based on hydrophobic interactions, hydrogen bonding, van der Waal interactions or pore-filling. In addition, some of the sorbents have been reported to impart selectivities based on acidity, basicity, and polarity (Kang et al 2009;Chigome et al 2011;Wardencki et al 2007;Fontanals et al 2007;Kloskowski et al 2009). …”

Tailor-made molecularly imprinted polymers for dimethoate and deltamethrin recognition: synthesis, characterization and chromatographic evaluation

“…More recently, much attention has been devoted to the use of molecular imprinting for the development of new adsorbents for solid phase extraction (SPE) [5,10,11,13] since the coupling of MIPs with SPE combines the advantages of both enhancement of template molecule recognition and traditional separation methods. Therefore, molecularly imprinted solid phase extraction (MISPE) combines the high specificity, selectivity and sensitivity related to molecular recognition mechanisms with the high resolving capacity of separation methods.…”

“…The resulting polymer must be grounded and sieved in order to achieve particles with an appropriate diameter for this application, followed by a subsequent washing procedure which must be able to clean the MIP cavities and minimizing the template bleeding. MIPs have been developed for a variety of applications including chromatography [6,7], catalysis [8,9], solid-phase extraction [5,[10][11][12][13], sensor technology [14][15][16] and drug delivery and discovery processes [17,18].…”