Breast Cancer is the second most common malignancy among Indian women accounting for 19-34%, next to cervical cancer. By early detection, understanding its pathogenesis and morphological features of the associated risk factors, one can prevent mortality against breast cancer. In India, high mortality is due to late diagnosis, poverty, fear and denial as majority of the patients present their condition in advanced or metastatic stage. The various risk factors associated with breast cancer include increasing age, geographical location, reproductive factors like early menarche or late menopause, family history, genetic mutations, nulliparity, avoiding breast-feeding, previous history of benign breast disease, exposure to radiations, use of exogenous hormones, obesity, dense breast tissue, sedentary lifestyle, smoking and. The aim of the present study was to assess the prevalence of associated risk factors of breast cancer in pre-menopausal and post-menopausal women of Hyderabad. A survey on 152 cancer women and 150 non-cancer women was done. A well structured questionnaire was employed to interview the subjects about their age, BMI, family history, reproductive health, diet and lifestyle. The data so collected was subjected to statistical analysis using chi square test. The results showed a positive correlation between breast cancer risk and age, increased BMI, family history, early marriage, late childbirth, consumption of exogenous hormones and breast-feeding (p<0.05). An awareness was also done through an illustrative brochure to educate the women about early detection of breast cancer, to implement healthy lifestyle interventions, importance of breast-feeding and poor impact of westernization of lifestyle. Thus, it was concluded from our study that there is a great impact of hormone-related factors and family history in the development of breast cancer.I. INTRODUCTION The mammary gland is a unique organ that undergoes extensive remodeling and differentiation even in adults. Hormonal changes in each menstrual cycle induce waves of proliferation in the mammary epithelium, whereas pregnancy leads to extensive ductal branching and alveogenesis [1]. Breast cancer starts when cells in the breast begin to grow out of control. These cells usually form a tumor that can often be seen on an x-ray or felt as a lump [2]. Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide, accounting for 23% (1.38 million) of the total new cancer cases and 14% (458,400) of the total cancer deaths in 2008 [3]. Increasing trends in developing areas are often considered the result of the 'westernisation' of lifestyles, an ill-defined surrogate for changes in factors such as childbearing, dietary habits and exposure to exogenous oestrogen, towards a distribution closer in profile to that of women in industrialised countries. As a consequence of changing exposures to reproductive and nutrition-related determinants over time, women are at increasingly high risk of breast cance...