Progress in nanomaterials-based electrochemical biosensors for the detection of interleukins

Ou, Lingbin

doi:10.20964/2022.04.37

Cited by 4 publications

(4 citation statements)

References 53 publications

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“…A general review of recent advances and possibilities with electrochemical biosensors for cytokine profiling has been published [ 48 ]. In addition, recent progress in nanomaterial-based electrochemical biosensors for the detection of interleukins has also been reviewed [ 49 ]. A recent example of electrochemical biosensors for ILs related to IBD is the impedimetric immunosensor reported by Frias et al [ 50 ] for IL-10, an interleukin secreted in patients at the early stage of inflammation.…”

Section: Gastrointestinal Microbiomementioning

confidence: 99%

Electrochemical (Bio)Sensing Devices for Human-Microbiome-Related Biomarkers

Sánchez‐Tirado

Agüı́

González‐Cortés

et al. 2023

Sensors

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The study of the human microbiome is a multidisciplinary area ranging from the field of technology to that of personalized medicine. The possibility of using microbiota biomarkers to improve the diagnosis and monitoring of diseases (e.g., cancer), health conditions (e.g., obesity) or relevant processes (e.g., aging) has raised great expectations, also in the field of bioelectroanalytical chemistry. The well-known advantages of electrochemical biosensors—high sensitivity, fast response, and the possibility of miniaturization, together with the potential for new nanomaterials to improve their design and performance—position them as unique tools to provide a better understanding of the entities of the human microbiome and raise the prospect of huge and important developments in the coming years. This review article compiles recent applications of electrochemical (bio)sensors for monitoring microbial metabolites and disease biomarkers related to different types of human microbiome, with a special focus on the gastrointestinal microbiome. Examples of electrochemical devices applied to real samples are critically discussed, as well as challenges to be faced and where future developments are expected to go.

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Section: Gastrointestinal Microbiomementioning

confidence: 99%

Electrochemical (Bio)Sensing Devices for Human-Microbiome-Related Biomarkers

Sánchez‐Tirado

Agüı́

González‐Cortés

et al. 2023

Sensors

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“…A general review of recent advances and possibilities of electrochemical biosensors for cytokine profiling has been published [46]. In addition, recent progress in nanomaterials-based electrochemical biosensors for the detection of interleukins has also been reviewed [47]. A recent example of electrochemical biosensors for ILs related to IBD is the impedimetric immunosensor reported by Frias et al [48] for IL-10, an interleukin secreted in patients at the early stage of inflammation.…”

Section: Gastrointestinal Microbiomementioning

confidence: 99%

“…An overview of electrochemical sensors targeting salivary biomarkers was published by Mani et al [96]. Several electrochemical biosensors have been developed for the detection of ILs [97] and specifically for IL-8, as a biomarker of oral cancer and other types of cancer. The normal concentration of IL-8 in human saliva is in the 200 -300 pg mL -1 range, whereas patients suffering from oral cavity and oropharyngeal squamous cell carcinoma have IL-8 concentrations higher than 720 pg mL -1 [98,99].…”

Section: Oral Microbiomementioning

confidence: 99%

Electrochemical (Bio)Sensing Devices for Human Microbiome Related Biomarkers

Sánchez‐Tirado¹,

Agüı́²,

González‐Cortés³

et al. 2022

Preprint

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The study of the human microbiome is a multidisciplinary area that affects from the field of technology to that of personalized medicine. The possibility of using microbiota biomarkers for the improvement in the diagnosis and monitoring of diseases (e.g. cancer), health conditions (e.g. obesity) or clinical parameters (e.g. ageing) has aroused great expectations, also in the scope of bio-electroanalytical chemistry. The well-known advantages of electrochemical transduction: high sensitivity, rapid response and possibility of miniaturization, together with the potential of new nanomaterials to improve both the design of electrode platforms and the performance of the resulting electrochemical biosensors make presumably a huge development in the next few years providing a better understanding of human microbiome entities. In this review article, the recent applications of electrochemical (bio)sensors for monitoring microbial metabolites and biomarkers of diseases related to different types of the human microbiome, with a special focus on the gastrointestinal microbiome, are reviewed. Examples of electrochemical devices applied to real samples are critically discussed as well as the challenges and prospects to be faced.

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“…Pei et al [25] prepared an electrochemical immunosensor for the quantitative detection of hepatitis B surface antigen using Au NPs loaded onto polypyrrole nanosheets as a platform and an Rh nucleus and Pt shell loaded onto amino-functionalized graphene nanosheets as markers. Nanomaterials are widely used in biological immunosensors because they can be used as enzyme carriers or signal markers of redox reaction reporters and electrode active substances [26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical biosensor based on antibody-modified Au nanoparticles for rapid and sensitive analysis of influenza A virus

Bao

Yang

et al. 2023

Ionics

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To cope with the easy transmissibility of the avian influenza A virus subtype H1N1, a biosensor was developed for rapid and highly sensitive electrochemical immunoassay. Based on the principle of specific binding between antibody and virus molecules, the active molecule-antibody-adapter structure was formed on the surface of an Au NP substrate electrode; it included a highly specific surface area and good electrochemical activity for selective amplification detection of the H1N1 virus. The electrochemical test results showed that the BSA/H1N1 Ab/Glu/Cys/Au NPs/CP electrode was used for the electrochemical detection of the H1N1 virus with a sensitivity of 92.1 µA (pg/mL) −1 cm 2 , LOD of 0.25 pg/ml, linear ranges of 0.25-5 pg/ mL, and linearity of (R 2 = 0.9846). A convenient H1N1 antibody-based electrochemical electrode for the molecular detection of the H1N1 virus will be of great use in the field of epidemic prevention and raw poultry protection.

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Progress in nanomaterials-based electrochemical biosensors for the detection of interleukins

Cited by 4 publications

References 53 publications

Electrochemical (Bio)Sensing Devices for Human-Microbiome-Related Biomarkers

Electrochemical (Bio)Sensing Devices for Human-Microbiome-Related Biomarkers

Electrochemical (Bio)Sensing Devices for Human Microbiome Related Biomarkers

Electrochemical biosensor based on antibody-modified Au nanoparticles for rapid and sensitive analysis of influenza A virus

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