severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, has spread globally, leading to more than 2 million confirmed cases (with the true prevalence of infection unknown but certainly much higher) and nearly 200,000 deaths. 1 In the early stages of the pandemic, cases were largely concentrated in the Wuhan province of China, and subsequently northern Italy, with the World Health Organization (WHO) labelling Europe as the epicenter of the pandemic as recently as March 13th. 2 However, as the pandemic progressed, the epicenter moved to the United States, with case numbers surpassing those in China by March 26th, and at the time of writing, standing at nearly four times the total confirmed cases of any other country. 1 It seems clear that the United States was not only ill-prepared and poorly positioned to deal with COVID-19, 3 but also uniquely susceptible to the spread of this illness. The rapid increase in cases, the escalating pressures on hospitals, and the latest modelling estimates suggest that the United States will bear the brunt of COVID-19 related harm as compared to many other high-income nations. It is prudent that we ask why this might be the case, particularly considering the status of the United States as the world's wealthiest country. While the predominant focus of public debate has been on political decision-making as the pandemic unfolded, this narrative fails to acknowledge additional longstanding exacerbating features in the United States that laid the ground for greater spread and slower containment of SARS-CoV-2. As with any such event, assessing the precise causes is a complex issue, but there are two important trends that we consider central to the United States'