2024
DOI: 10.3389/fphar.2024.1327502
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Progress in the study of reproductive toxicity of platinum-based antitumor drugs and their means of prevention

Zhan Jin,
Liu Zhao-Xia,
Peng Fan-Ke
et al.

Abstract: Platinum-based antitumor drugs are broad-spectrum agents with unique mechanisms of action. Combination chemotherapy regimens based on platinum drugs are commonly used in cancer treatment. However, these drugs can cause various adverse reactions in the human body through different routes of administration, including reproductive toxicity, genetic toxicity, and embryonic developmental toxicity. Preventing adverse effects is crucial to enhance patients' quality of life and reduce healthcare costs. This article di… Show more

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