Progress on dual harmonic acceleration on the isis synchrotron

Seville, A.; Adams, D.; Appelbee, C.; Bayley, D.; N.E.Farthing,; Gardner, Ian; Glover, M.; Pine, Ben; Thomason, J. W. G.; Warsop, C M

doi:10.1109/pac.2007.4440852

Cited by 8 publications

(5 citation statements)

References 3 publications

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“…-must be able to adjust to and stabilise at the correct field settings in around a millisecond. This is not beyond the realms of existing technology given that, for example, the ISIS Rapid Cycling Synchrotron (RCS) ramps up in energy at a rate of 70 MeV/ms [48,49]. However, the difference for a clinical beamline is that the magnets must adjust and then stabilise rather than cycling continuously over a range of fields.…”

Section: Magnet Switchingmentioning

confidence: 99%

Technical challenges for FLASH proton therapy

Owen²,

et al. 2020

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There is growing interest in the radiotherapy community in the application of FLASH radiotherapy, wherein the dose is delivered to the entire treatment volume in less than a second. Early pre-clinical evidence suggests that these extremely high dose rates provide significant sparing of healthy tissue compared to conventional radiotherapy without reducing the damage to cancerous cells. This interest has been reflected in the proton therapy community, with early tests indicating that the FLASH effect is also present with high dose rate proton irradiation.In order to deliver clinically relevant doses at FLASH dose rates significant technical hurdles must be overcome in the accelerator technology before FLASH proton therapy can be realised. Of these challenges, increasing the average current from the present clinical range of 1-10 nA to in excess of 100 nA is at least feasible with existing technology, while the necessity for rapid energy adjustment on the order of a few milliseconds is much more challenging, particularly for synchrotron-based systems. However, the greatest challenge is to implement full pencil beam scanning, where scanning speeds 2 orders of magnitude faster than the existing state-of-the-art will be necessary, along with similar improvements in the speed and accuracy of associated dosimetry. Hybrid systems utilising 3D-printed patient specific range modulators present the most likely route to clinical delivery. However, to correctly adapt and develop existing technology to meet the challenges of FLASH, more pre-clinical studies are needed to properly establish the beam parameters that are necessary to produce the FLASH effect.

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Section: Magnet Switchingmentioning

confidence: 99%

Technical challenges for FLASH proton therapy

Owen²,

et al. 2020

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“…Preliminary RCS designs [450] have concentrated on achieving the necessary acceleration and bunch compression with present-day, cost-effective RCS technology, e.g., dipole magnets with a maximum field of 1.2 T, an RF system similar to that used at ISIS [462] and long straight sections for injection, extraction, RF and collimation. An RCS design based on injection from the 5SP 3.2 GeV booster with harmonic number 9 and 4 MW total beam power (the last entry in Table XXXIX) has been investigated.…”

Section: A Dedicated Neutrino Factory Boostermentioning

confidence: 99%

Interim Design Report

Abrams¹,

Agarwalla²,

Alekou³

et al. 2011

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“…The ISIS synchrotron runs essentially in the h = 2 mode, although with the dual harmonic RF running [7] as described below an h = 4 component is added. Superperiods (SPs) 0 and 1 are used for charge exchange injection and extraction respectively, with SP1 also incorporating the collectors for beam collimation.…”

Section: Acceleratorsmentioning

confidence: 99%

ISIS - pulsed neutron and muon source

Findlay

2007

2007 IEEE Particle Accelerator Conference (PAC)

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The ISIS pulsed neutron and muon source is described. Up to now the accelerators have delivered a 145-160 kW proton beam at 50 pps to a tungsten neutron-producing target preceded by a graphite muon-producing intermediate target. However a second target station is now being constructed, and the beam power from the accelerators is being increased so that the first target station will not suffer in performance when the beam has to be divided between two target stations.

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Progress on dual harmonic acceleration on the isis synchrotron

Cited by 8 publications

References 3 publications

Technical challenges for FLASH proton therapy

Technical challenges for FLASH proton therapy

Interim Design Report

ISIS - pulsed neutron and muon source

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