Progress on Photothermal Conversion in the Second NIR Window Based on Conjugated Polymers

Abstract

In view of the distinct advantages of deep tissue penetration of NIR‐II light and the outstanding biocompatibility of conjugated polymers, the design and development of conjugated polymers with the ability of photothermal conversion in NIR‐II window are extremely important for biomedical applications. In this focus review, based on the excellent features of photothermal conversion and NIR‐II light, several key factors and related principles of developing conjugated photothermal polymers are proposed and discussed systematically. Accordingly, some illuminating conjugated NIR‐II photothermal polymers are exemplified and highlighted. This Focus Review aims to provide another perspective for constructing highly efficient NIR‐II photothermal conversion to expand the biomedical applications of conjugated polymers.

Polyaniline Nanovesicles for Photoacoustic Imaging‐Guided Photothermal‐Chemo Synergistic Therapy in the Second Near‐Infrared Window

“…[ 11,15 ] Analogously, combined photothermal therapy (PTT) in the NIR‐II window can offer more efficient tissue penetration by alleviating light attenuation. [ 16 ] Furthermore, NIR‐II light has higher maximum permissible exposure to human tissues than NIR‐I light, making phototheranostics in the NIR‐II window more promising. [ 11,15,16 ]…”

“…[ 16 ] Furthermore, NIR‐II light has higher maximum permissible exposure to human tissues than NIR‐I light, making phototheranostics in the NIR‐II window more promising. [ 11,15,16 ]…”

Recent Advances in Nanomaterials-Based Chemo-Photothermal Combination Therapy for Improving Cancer Treatment

“…To achieve higher photothermal conversion efficiency, conjugated polymers with narrow energy band gap are highly desired as they are expected to have sharper adsorption peaks to get greater heat generation (He Y. L. et al, 2018). The concept of donor-acceptor (D-A) has been widely applied for designing conjugated polymer-based field-effect transistors and organic photovoltaics.…”

A Water-Soluble Photothermal Host–Guest Complex with pH-Sensitive Superlarge Redshift Absorption

“…Supporting Information is available. 1 H NMR spectra of ACAT and ACAT-CD; ESI-MS spectra of ACAT; FT-IR spectra of ACAT-CD and ACAT; TGA β-CD, ACAT-CD and ACAT; Fluorescence spectrum of ACAT-CD; Proposed mechanism for ACAT in various oxidized states at acidic and basic environment; The calculation of photothermal conversion efficiency; H&E staining experiment.…”

“…Owing to less absorption by water and hemoglobin, near infrared (NIR) light relative to other wavelengths is showing great potentials in clinical diagnosis and treatment in deeper tissues. [1][2][3][4][5] Amongst those reliable methods to utilize NIR light, photothermal conversion via non-irradiative emission has been regarded as an attractive choice with the highest quantum efficiency. [6][7][8][9][10] It can generate hyperthermia in diseased tissues, allowing photothermal conversion mainly in tumor tissues.…”