Progress on transition metal catalyzed asymmetric hydroesterification, hydrocarboxylation, and hydroamidation reactions of olefins

Abstract

This review provides a brief summary of the development of transition metal catalyzed asymmetric hydrocarboxylation, hydroesterification, and hydroamidation of olefins with CO and its surrogates.

Palladium‐Catalyzed Enantioselective Hydrofunctionalization of Alkenes: Recent Advances

“…[68] Recently, Shi and coworkers reported a leading review on transition metal-catalyzed asymmetric hydrocarboxylation, hydroesterification and hydroamidation of olefins. [69] Nevertheless, a brief summary of Palladium-catalyzed asymmetric hydrocarbonylation of alkenes in the past decade is still included in this review.…”

“…In the past decades, remarkable progresses have been made in Palladium catalyzed asymmetric hydrocarbonylation of alkenes, [67] although high regio‐ and enantioselectivities can only be obtained from a limited number of styrenes in high temperatures or pressures [68] . Recently, Shi and coworkers reported a leading review on transition metal‐catalyzed asymmetric hydrocarboxylation, hydroesterification and hydroamidation of olefins [69] . Nevertheless, a brief summary of Palladium‐catalyzed asymmetric hydrocarbonylation of alkenes in the past decade is still included in this review.…”

Development of Efficient Ru/Deep Eutectic Solvent Catalytic System for Alkoxycarbonylation of Alkene without Acid Additives

“…Carboxylic esters are essential bulk chemicals that find wide‐ranging applications in drug intermediates, plasticisers, lubricants, and various other fields [1–2] . Transition metal‐catalysed alkoxycarbonylation (also known as hydroesterification) with alkenes, alcohols and CO is one of the most effective methods to synthesise these high‐value‐added esters owing to the perfect atom economy and wide availability of raw materials [3–5] . To date, many transition metals, including Rh, [6–7] Ru, [8–9] Pt, [10] Co, [11] and Pd, [12–14] have been found to be active catalysts in the alkoxycarbonylation of alkenes.…”

“…[1][2] Transition metal-catalysed alkoxycarbonylation (also known as hydroesterification) with alkenes, alcohols and CO is one of the most effective methods to synthesise these high-value-added esters owing to the perfect atom economy and wide availability of raw materials. [3][4][5] To date, many transition metals, including Rh, [6][7] Ru, [8][9] Pt, [10] Co, [11] and Pd, [12][13][14] have been found to be active catalysts in the alkoxycarbonylation of alkenes. Among these metal catalyst systems, the Pd-based homogeneous system has gained significant attention due to its high catalytic activity and versatile substrate adaptability.…”

Stereospecific Acylative Suzuki–Miyaura Cross-Coupling: General Access to Optically Active α-Aryl Carbonyl Compounds

“…Over time, synthetic approaches that are based on either enolates (Figure B,a) or α-halo carbonyl compounds (Figure B,b) have played a pivotal role in the advancement of the discipline with the help of transition metal-based asymmetric catalysis. , More recently, orthogonal approaches that exploit the elevated reactivity of an acyl donor have successfully furnished the target structure via stereoselective introduction of a benzylic moiety (Figure B,c) . These methods, in combination with other types of catalytic approaches, have significantly contributed to providing an access to valuable α-aryl carbonyl compounds in an enantiopure form …”