Progress Toward Poliomyelitis Eradication — Worldwide, January 2021–March 2023

Progress Toward Poliomyelitis Eradication — Worldwide, January 2022–December 2023

“…The GPEI goal to interrupt all types of poliovirus transmission was not achieved in December 2023 ( 5 ). This report summarizes the status of polio eradication during January 1, 2022–December 31, 2023, and updates previous reports ( 1 , 6 ).…”

“…The 2021–2022 WPV1 outbreak in Africa included one WPV1 case in Malawi (November 2021) and eight cases in one province in Mozambique in 2022 ( 1 ). All Mozambique cases were genetically linked to the Malawi case and the Malawi case was linked to Pakistan.…”

“…Since the establishment of the Global Polio Eradication Initiative (GPEI) in 1988, wild poliovirus (WPV) types 2 and 3 have been eradicated, and WPV type 1 (WPV1) remains endemic only in Afghanistan and Pakistan. In November 2021, a WPV1 outbreak genetically linked to Pakistan was detected in the southeastern African country of Malawi and spread to neighboring Mozambique in 2022 ( 1 ). Circulating vaccine-derived polioviruses (cVDPVs) can emerge and cause outbreaks in underimmunized populations when attenuated oral poliovirus vaccine (OPV) strains undergo prolonged person-to-person transmission that allows genetic mutation and recombination to occur, resulting in a reverted poliovirus with the ability to cause paralysis ( 2 ).…”

Polio Eradication: Status, Struggles and Strategies

“…1). The majority of cVDPV2 cases have been reported from the African region, and international travel has resulted in the spread to countries that have long been free of poliovirus transmission: in 2022, a paralytic case was reported in New York state in an unimmunized adult, 17 and cVDPV2 isolates were detected in wastewater in the United Kingdom, Canada and Israel, 18,19 among other countries. These events illustrate the serious risk of the global spread of polioviruses.…”

Poliovirus: una actualización en el esquema de vacunas

“…66-83 Journal Scientific MQRInvestigar 76 cobertura estimada con 1 dosis completa o 2 fraccionadas de IPV en los países que usan OPV fue del 79%. En los países con transmisión endémica de WPV la cobertura estimada de Pol3 en 2021 fue del 71% en Afganistán y de fIPV del 67%; 83% en Pakistán tanto para Pol3 como para fIPV; mientras que, en Malawi la cobertura para Pol3 fue del 89% y para fIPV del 92% (Greene et al, 2019;Lee et al, 2023). Sin embargo, en cifras generales para el 2022 el 84% de los lactantes a nivel global recibieron 3 dosis de la vacuna contra el polio y el mismo porcentaje había recibido la primera dosis de IPV en países que todavía utilizan OPV (OMS, 2023b).…”