Progression of atrial fibrillation after a failed initial ablation procedure in patients with paroxysmal atrial fibrillation: a randomized comparison of antiarrhythmic drug therapy vs re-ablation

Покушалов, Е А; Романов, А Б; Melis, Mirko De; Artyomenko, Sergey; Baranová, Věra; Losik, Denis; Байрамова, С. А.; Karaskov, Alexander; Mittal, Suneet; Steinberg, Jonathan S.

doi:10.1093/eurheartj/eht309.2805

Cited by 2 publications

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“…Eight studies (14,15,30,32,35,41,43,44) were included in the second group, and the main features of these studies are summarized in Table 2. The forest plot assessing the percentage of progression reported in the studies is shown in Figure 2.…”

Section: Resultsmentioning

confidence: 99%

A Systematic Review on the Progression of Paroxysmal to Persistent Atrial Fibrillation

Proietti

Hadjis

AlTurki

et al. 2015

JACC: Clinical Electrophysiology

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The progression from paroxysmal atrial fibrillation (AF) to persistent or long-term persistent forms has recently gained increasing attention. A growing amount of data has shown a significant morbidity and mortality associated with the transition. The aim of our systematic review was to assess the evidence regarding AF progression rates with different management approaches. Electronic databases were searched by using text words and relevant indexing to capture data on AF progression. Studies that considered progression from paroxysmal AF to a persistent or permanent form were included. The papers collected were divided into 2 groups: 1) general population studies (with almost exclusively medical therapy); and 2) studies that consider progression of AF subsequent to AF ablation. Twenty-one studies were included in the first group and 8 in the second group. In the first group, percentage of AF progression at 1 year ranged from 10% to 20%. Studies that included a longer follow-up detected a higher percentage of progression (from 50% to 77% after 12 years). In patients treated with catheter ablation, the percentage of progression was significantly lower (from 2.4% to 2.7% at 5 years' follow-up). The percentage of progression after catheter ablation did not change according to duration of follow-up. AF ablation is associated with significantly reduced progression to persistent forms compared with studies in the general population. Prevention of long-term AF progression may be a clinically relevant outcome after AF ablation. Further research is required to determine whether delaying progression of AF by catheter ablation reduces morbidity and mortality.

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Section: Resultsmentioning

confidence: 99%

A Systematic Review on the Progression of Paroxysmal to Persistent Atrial Fibrillation

Proietti

Hadjis

AlTurki

et al. 2015

JACC: Clinical Electrophysiology

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“…Нельзя не признать, исходя из литературных данных, что до сих пор отсутствует однозначное мнение о преимуществах влияния на частоту трансформации пароксизмальной ФП в постоянную форму различных лекарственных препаратов (ААТ, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента, блокаторы кальциевых каналов, статины), электрической конверсии с целью восстановления синусового ритма перед фармакологической, о качестве превентивной терапии заболеваний сердца (ИБС, гипертонической болезни, патологии миокарда и клапанов) и сопутствующих заболеваний различного характера [5,12,4,15,16].…”

Section: Discussionunclassified

Estimation of Prognostic Possibilities of Paroxysmal Atrial Fibrillation Transformation in the Permanent Form in Medication Treated Ischemic Heart Disease Patients

Иванов¹,

Бондаренко²

2017

Transl. med. (Print)

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Objective. Estimation of individual risk transformation of paroxysmal atrial fibrillation (AF) in the permanent form in medication treated ischemic heart disease (IHD) patients. Design and Methods. Analysis includes 149 IHD patients with paroxysmal AF. Their treatment consisted of drug combination usually used in IHD patients including beta-blockers. No other medications with antiarrhythmic properties were used. Comparisons between the means of the values were made by Student's test and exact Fisher method. Selection of the factors most informative for risk of the paroxysmal AF transformation in the permanent form was realized with the logistic discriminant analysis. Results. Within three-years follow-up paroxysmal AF remained in 102 (68%) patients while in 47 (32%) cases it transformed in the permanent form of AF. It is revealed that risk of the paroxysmal AF transformation is associated with increase of aging, dimension of the left atrium, atrial ectopic activity and decrease of the left ventricle ejection fraction. Conclusion. The offered estimation of the individual paroxysmal AF transformation risk for IHD patients in the permanent form of AF during three-years follow-up period is characterized by high prognostic accuracy: 97% for preservation of paroxysmal AF, and 93% for its transformation in the permanent form.

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Progression of atrial fibrillation after a failed initial ablation procedure in patients with paroxysmal atrial fibrillation: a randomized comparison of antiarrhythmic drug therapy vs re-ablation

Cited by 2 publications

References 0 publications

A Systematic Review on the Progression of Paroxysmal to Persistent Atrial Fibrillation

A Systematic Review on the Progression of Paroxysmal to Persistent Atrial Fibrillation

Estimation of Prognostic Possibilities of Paroxysmal Atrial Fibrillation Transformation in the Permanent Form in Medication Treated Ischemic Heart Disease Patients

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