Progression of Central-peripheral Band and Traction Bronchiectasis Clusters Leading to Chronic Respiratory Failure in a Patient with Fibrotic Pulmonary Sarcoidosis

Sawahata, Michiru; Shijubo, Noriharu; Johkoh, Takeshi; Kawanobe, Takeshi; Fujiki, Yasumaro; Bando, Masashi; Hagiwara, Koichi; Takemura, Tamiko; Konno, Satoshi; Yamaguchi, Tetsuo

doi:10.2169/internalmedicine.4862-20

Cited by 7 publications

(8 citation statements)

References 10 publications

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“…При ДН рекомендуется: • дифференцированный подход к лечению на основании данных спирометрии и пульсоксиметрии. Бронхолитическая терапия рекомендуется при доказанном спирометрически саркоидозе, осложненном бронхообструктивном синдроме [157,158].…”

Section: дыхательная недостаточность и легочная гипертензияunclassified

“…При саркоидозе, осложненном ДН, наличии ограничительных нарушениях вентиляции и десатурации рекомендуется низкопоточная оксигенация (табл. 3) [157,158].…”

Section: уровень убедительности рекомендаций C (уровень достоверности...unclassified

“…• дифференцированный подход к лечению на основании данных спирометрии и пульсоксиметрии. При саркоидозе, осложненном тяжелой ДН, рекомендуется неинвазивная вентиляция легких [157,158].…”

Section: уровень убедительности рекомендаций C (уровень достоверности...unclassified

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Sarcoidosis: federal clinical guidelines for diagnosis and treatment

Чучалин

Avdeev

Айсанов

et al. 2022

Pulʹmonologiâ (Mosk.)

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Sarcoidosis is a multi-organ granulomatosis of unknown origin. Modern diagnostic methods allow detecting this disease at an early stage. The absence of specific markers requires a comprehensive approach to diagnosis based on comparison of radiation, clinical, morphological and functional data. The course of sarcoidosis without damage to the respiratory system presents significant difficulties. It is extremely important to understand the time and means of starting Sarcoidosis’s treatment to avoid the early initiation of hormones and cytostatics and, on the other hand, to timely respond to progression and threatening conditions. Methods. Clinical recommendations are based on the analysis of Russian and English publications of the latest sarcoidosis research. The target audience of these clinical guidelines are therapists, general practitioners, pulmonologists, TB doctors, rheumatologists, dermatologists, radiation diagnosticians, immunologists, and clinical pharmacologists. Each thesis-recommendation for diagnosis and treatment is evaluated on an 1 to 5 scale of levels of evidence and an A, B, C scale of the grades of recommendations. The clinical guidelines also contain comments and explanations for the theses-recommendations, diagnostic algorithms, treatment strategies, reference materials on the use of recommended drugs. Conclusion. Current information on epidemiology, clinical manifestations, diagnosis and management strategies for patients with sarcoidosis are covered in the presented clinical guidelines. Approved by the decision of the Scientific and Practical Council of the Ministry of Health of the Russian Federation (2022).

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Section: дыхательная недостаточность и легочная гипертензияunclassified

Section: уровень убедительности рекомендаций C (уровень достоверности...unclassified

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Sarcoidosis: federal clinical guidelines for diagnosis and treatment

Чучалин

Avdeev

Айсанов

et al. 2022

Pulʹmonologiâ (Mosk.)

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“…In case of bronchiectasis, it may be normal but some cases may have enlarged peripheral cysts and mild calcification of hilar mediastinal lymphadenopathy [8,9].…”

Section: Radiological Evaluationmentioning

confidence: 99%

The clinical and functional characteristics of bronchiectasis among tuberculosis patients in Upper Egypt: a single-center study

et al. 2022

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Background Tuberculosis (TB) is considered one of the most common causes of bronchiectasis. Bronchiectasis increases clinical and financial burden of patients with TB. Here, we aim to assess the prevalence of bronchiectasis and its characteristics in patients with TB. Results Over 1 year duration, 85 patients with confirmed TB were enrolled in the study. Those patients were clinically, laboratory, and radiologically evaluated. Any patient with other chest diseases was excluded from the study. Out of those patients, 19/85 (22.4%) patients had bronchiectasis. It was found that patients with bronchiectasis had higher frequency of urban residence, current cigarette or goza smoking, and diabetes mellitus. Hemoptysis and expectoration were the most frequent symptoms. Pulmonary function tests were significantly impaired in patients with bronchiectasis. Disease burden was significantly higher among bronchiectasis group in form of frequent hospitalization, longer hospital stay, and need of oxygen therapy. Conclusion Bronchiectasis is not uncommon among TB patients. Co-existence of bronchiectasis with TB has distinctive clinical, and functional characteristics that increase the burden of the diseases in the form of prolonged hospital stay and higher utilization of antibiotics and oxygen therapy. Smoking in tuberculous patients may is significantly associated with bronchiectasis.

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“…Uvođenje novih radioloških metoda, doprinosi boljem i češćem prepoznavanju ove bolesti. Incidenca iznosi 1,3 na 1000 stanovnika [2] sa većom prevalencijom kod žena i starijih osoba [3].…”

Section: Uvodunclassified

Airway inflammation in patients with bronchiectasis

Đurđević¹,

Milenković²,

Janković³

et al. 2021

Halo 194

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Bronchiectasis is a chronic lung disease characterized by an abnormal dilation of the bronchial lumen caused by weakening or destruction of the muscle or elastic components of the bronchial wall, decreased mucous clearance and frequent infections of the respiratory tract. The golden standard for bronchiectasis diagnosis is high-resolution computed tomography (HRCT) of the chest. Inflammation holds a central role in the development of structural lung changes, as well as airway and lung parenchyma damage. Infection and colonization of the respiratory tract contribute to increased inflammation and further damage to the lung. Upon entry into the respiratory tract, the pathogens activate epithelial cells, macrophages and dendritic cells. Activated inflammatory cells secrete chemical mediators which activate the immune response and thus allow the phagocytosis of pathogens. Early diagnosis, appropriate treatment and interruption of the vicious circle between infection and inflammation in patients suffering from bronchiectasis, prevent the development of structural changes to the airways.

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Progression of Central-peripheral Band and Traction Bronchiectasis Clusters Leading to Chronic Respiratory Failure in a Patient with Fibrotic Pulmonary Sarcoidosis

Cited by 7 publications

References 10 publications

Sarcoidosis: federal clinical guidelines for diagnosis and treatment

Sarcoidosis: federal clinical guidelines for diagnosis and treatment

The clinical and functional characteristics of bronchiectasis among tuberculosis patients in Upper Egypt: a single-center study

Airway inflammation in patients with bronchiectasis

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