Progression of depression and anxiety symptoms in pregnancies conceived by assisted reproductive technology in the United States

Simoni, Michael; Gilstad‐Hayden, Kathryn; Naqvi, Syed; Pal, Lubna; Yonkers, Kimberly A.

doi:10.1080/0167482x.2021.1971193

Cited by 6 publications

(3 citation statements)

References 40 publications

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Section: Discussionmentioning

confidence: 99%

“…Despite the well-known effect of infertility and its treatment on mental health, only a few studies have examined the association between the method of conception and anxiety or depression during pregnancy [ 8 ]. A recent review of the available literature on the subject concluded that the evidence does not support IVF as a factor associated with perinatal affective symptoms [ 8 ]. In terms of perinatal depression, a large longitudinal study from Sweden with 3283 women found no link between IVF and natural conception [ 9 ], while smaller studies found that IVF groups have both higher [ 10 ] and lower rates of antenatal depression [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…A study that examined depression during pregnancy at different time points in both women who conceived via ART and naturally showed that the prevalence was similar, although the ART group had different rates of change in depressive symptoms through gestation [ 8 ]. Another meta-analysis of eight studies found a comparable prevalence of postpartum depression in the IVF and natural conception groups [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

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Is Conception by Means In Vitro Fertilization Associated With Increased Risk of Antenatal Anxiety and Depression?

Arvanitidou¹,

Kalaitzopoulos²,

Samartzis³

et al. 2023

Cureus

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Mental health during pregnancy is a very important public health issue with negative effects on both maternal and child outcomes. The aim of our study is to examine the possible association between conception via in vitro fertilization (IVF) and anxiety or depression during the third pregnancy trimester in the Greek population during the years of financial crisis. Materials and MethodsThis single-center prospective cohort study was conducted in a tertiary university hospital during the period 2017-2018. Pregnant women attending the Antenatal Care Program between 30th-32nd gestational week were asked to complete Hamilton Anxiety Rating Scale (HAM-A) and Beck Depression Inventory (BDI). A propensity score match for 10 variables was conducted in a 1:3 ratio. ResultsOf the 521 eligible patients, 446 women were included in our study. Four hundred fourteen of them conceived spontaneously, and 32 via IVF. After propensity score matching, 76 remained in the analysis, of whom 57 conceived spontaneously and 19 with IVF. The IVF group had a higher rate of anxiety (18.8%) and a lower rate of depression (9.4%) than the spontaneous conception group (13.5% and 13.5%, respectively), but the differences were not statistically significant before and after propensity score matching. ConclusionOur study showed that pregnancies after IVF had a higher incidence of antenatal anxiety and a lower incidence of antenatal depression in comparison to pregnancies that were conceived naturally, although the differences did not reach statistical significance.

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Section: Discussionmentioning

confidence: 99%