Progression of Hip Disease in Rheumatoid Arthritis

Bossingham, David; Schorn, D; Morgan, Graeme; Mowat, A G

doi:10.1093/rheumatology/17.3.170

Cited by 8 publications

(1 citation statement)

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“…Our investigation did not show any differences in the rate of bone defects in the femoral head between the groups. Disease activity in rheumatoid arthritis may therefore not be related to the degree of femoral head destruction 15 .…”

Section: Discussionmentioning

confidence: 99%

Comparing the Progression of Hip Joint Destruction in Patients with Rheumatoid Arthritis before and after Intervention with Methotrexate and Biologics DMARDs

Toyoshima

Sukezaki

et al. 2014

Showa Univ J Med Sci

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Abstract:We investigated hip joint destruction in patients with rheumatoid arthritis before and after the availability of methotrexate and biological disease-modifying anti-rheumatic drugs DMARDs in Japan. A total of 35 patients with 45 diseased joints underwent total hip arthroplasty from 1995 to 1999 Group A: 21 hips in 15 patients and from 2006 to 2010 Group B: 24 hips in 20 patients . We monitored the oral administration of therapeutic drugs and prednisolone, measured preoperative C-reactive protein CRP levels, estimated the Larsen grade and bone defects of the acetabulum oor using simple X-ray images, and calculated the bone defect rate of the femoral head. The intake of preoperative oral prednisolone was signi cantly less in Group B than in Group A P 0.05 , as were preoperative CRP levels P 0.05 .

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Section: Discussionmentioning

confidence: 99%