Progression of microalbuminuria in SHR is associated with diminished expression of proteins that belong to the receptor‐mediated endocytosis macromolecular complex
Abstract:Microalbuminuria is recognized to be a risk factor for cardiovascular and kidney disease and is associated with morbidity and mortality in hypertensive patients. It arises as a consequence of increased glomerular permeability and/or reduced tubular reabsorption. The aims of the present study were: (1) to analyze the temporal evolution and the pattern of urinary protein excretion in spontaneously hypertensive rats (SHR), and (2) to evaluate whether the expression of proteins implicated in receptor‐mediated endo… Show more
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