Progression of probable UIP and UIP on HRCT

Salvatore, Mary M.; Singh, Ayushi; Yip, Rowena; Fevrier, E.; Henschke, Claudia I.; Yankelevitz, David F.; Padilla, María

doi:10.1016/j.clinimag.2019.07.003

Cited by 12 publications

(14 citation statements)

References 12 publications

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“…Analysis of extent of high density areas allows the radiologist to provide a visual quantification of the amount of fibrosis ( 21 ). A grading system can provide a visual quantification of fibrosis ( 22 ). Follow up imaging can be used to assess the extent of conversion of normal lung to fibrotic lung.…”

Section: Usual Interstitial Pneumonitis (Uip)mentioning

confidence: 99%

“…Thirty five patients had HC on the initial CT scan of which 57% increased the extent of disease over 31 months, also progressive disease. Enlarged pulmonary artery and emphysema were associated with disease progression ( 22 ). Serial imaging is used to evaluate progression which is not necessarily discovered between the first and second HRCT scans.…”

Section: Usual Interstitial Pneumonitis (Uip)mentioning

confidence: 99%

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The Role of Radiology in Progressive Fibrosing Interstitial Lung Disease

et al. 2022

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In this article, we describe the role of radiology for diagnosis and follow-up of progressive fibrosing interstitial lung disease (PF-ILD). Patients with PF-ILD are at increased risk for early death without treatment. Clinical diagnosis of PF-ILD has been described in the literature. This manuscript reviews the radiographic diagnosis of PF-ILD and the unique CT characteristics associated with specific types of fibrosis. Ultimately, we believe that radiology has the potential to recognize progression early and thus make an important contribution to the multidisciplinary discussion for this important diagnosis.

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Section: Usual Interstitial Pneumonitis (Uip)mentioning

confidence: 99%

Section: Usual Interstitial Pneumonitis (Uip)mentioning

confidence: 99%

The Role of Radiology in Progressive Fibrosing Interstitial Lung Disease

et al. 2022

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“…62 In terms of the progression of the disease, a study by Salvatore et al intended to determine patterns of progression in patients with probable UIP patterns. 63 They reviewed clinical information for 103 patients with a working diagnosis of IPF. They found that among patients with an initial diagnosis of probable UIP, 47% of them progressed to a definite diagnosis of UIP.…”

Section: Usual Interstitial Pneumoniamentioning

confidence: 99%

High-Resolution Computed Tomography of Fibrotic Interstitial Lung Disease

Rodriguez

Ashby

Varela

et al. 2022

Semin Respir Crit Care Med

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While radiography is the first-line imaging technique for evaluation of pulmonary disease, high-resolution computed tomography (HRCT) provides detailed assessment of the lung parenchyma and interstitium, allowing normal anatomy to be differentiated from superimposed abnormal findings. The fibrotic interstitial lung diseases have HRCT features that include reticulation, traction bronchiectasis and bronchiolectasis, honeycombing, architectural distortion, and volume loss. The characterization and distribution of these features result in distinctive CT patterns. The CT pattern and its progression over time can be combined with clinical, serologic, and pathologic data during multidisciplinary discussion to establish a clinical diagnosis. Serial examinations identify progression, treatment response, complications, and can assist in determining prognosis. This article will describe the technique used to perform HRCT, the normal and abnormal appearance of the lung on HRCT, and the CT patterns identified in common fibrotic lung diseases.

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“…Combined pulmonary fibrosis and emphysema is an important radiographic diagnosis with significant centrilobular type emphysema and a UIP pattern (59). Radiologists should describe these findings as they are associated with an increased risk of lung cancer and will likely progress over time (60).…”

Section: Pulmonary Fibrosismentioning

confidence: 99%

Added benefits of early detection of other diseases on low-dose CT screening

Yip

Jirapatnakul

et al. 2021

Transl Lung Cancer Res

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Low-dose CT screening for lung cancer provides images of the entire chest and upper abdomen.While the focus of screening is on finding early lung cancer, radiology leadership has embraced the fact that the information contained in the images presents a new challenge to the radiology profession. Other findings in the chest and upper abdomen were not the reason for obtaining the screening CT scan, nor symptomprompted, but still need to be reported. Reporting these findings and making recommendations for further workup requires careful consideration to avoid unnecessary workup or interventions while still maximizing the benefit that early identification of these other diseases provided. Other potential findings, such as cardiovascular disease and chronic pulmonary obstructive diseases actually cause more deaths than lung cancer. Existing recommendations for workup of abnormal CT findings are based on symptom-prompted indications for imaging. These recommendations may be different when the abnormalities are identified in asymptomatic people undergoing CT screening for lung cancer. I-ELCAP, a large prospectively collected multi-institutional and multi-national database of screenings, was used to analyze CT findings identified in screening for lung cancer. These analyses and recommendations were made by radiologists in collaboration with clinicians in different medical specialties.

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Progression of probable UIP and UIP on HRCT

Cited by 12 publications

References 12 publications

The Role of Radiology in Progressive Fibrosing Interstitial Lung Disease

The Role of Radiology in Progressive Fibrosing Interstitial Lung Disease

High-Resolution Computed Tomography of Fibrotic Interstitial Lung Disease

Added benefits of early detection of other diseases on low-dose CT screening

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