Progression of renal allograft histology after renal transplantation in recurrent and nonrecurrent immunoglobulin A nephropathy

Jeong, Hyeon Joo; Park, Su Kil; Cho, Yong Mee; Kim, Myoung Soo; Kim, Yu Seun; Choi, Jung Yoon; Kim, Soon Il; Lim, Beom Jin

doi:10.1016/j.humpath.2008.03.003

Cited by 14 publications

(9 citation statements)

References 22 publications

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“…This is in accordance with large studies which reported major complication rate between 0.4 to 1 percent. [8] It is also in accordance with the view that it is ethically justifiable to perform protocol graft kidney biopsies both in clinical trials and routine care.…”

Section: Safety Of Protocol Kidney Biopsysupporting

confidence: 55%

“…Autopsy studies from cases without known renal disease report histologic IgANin 4-8%. [8] However, a gradual resolution of IgA deposits is expected to occur within 45 days following transplantation. In a study of 0-h renal biopsies, where 87% of transplants were from living donors, latent mesangial deposition of IgA was present in 16% of its cases.…”

Section: Discussionmentioning

confidence: 99%

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Immunoglobulin A (IgA) Nephropathy in Protocol Graft Kidney Biopsy done at six months Post Transplantation in a Tertiary Care Center Hospital of Nepal

Shrestha

Shah

2017

J Nobel Med Coll

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Section: Safety Of Protocol Kidney Biopsysupporting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Immunoglobulin A (IgA) Nephropathy in Protocol Graft Kidney Biopsy done at six months Post Transplantation in a Tertiary Care Center Hospital of Nepal

Shrestha

Shah

2017

J Nobel Med Coll

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“…However, with increasing graft survival, there have been increased opportunities to observe these conditions in late post-transplant biopsies, and they are often associated with graft dysfunction. For example, development of massive crescents in post-transplant IgA nephropathy or recurrent antineutrophil cytoplasmic antibody-associated glomerulonephritis may be a major contributor to graft dysfunction [46][47][48]. Additionally, recurrent focal segmental glomerulosclerosis can cause massive proteinuria.…”

Section: Non-rejection Conditionsmentioning

confidence: 99%

Diagnosis of renal transplant rejection: Banff classification and beyond

Jeong

2020

Kidney Res Clin Pract

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“…The results of renal transplantation in patients with IgAN have been differently estimated. Some investigators (10,11) reported a more favorable outcome of the renal allograft in patients with IgAN than in other transplant recipients, but others found that graft survival in an IgAN group was similar to that of non-IgAN renal transplant recipients (12)(13)(14). An analysis of the Eurotransplant registry data reported the outcome of 1207 patients with IgAN and 7935 other renal transplant recipients.…”

Section: Iganmentioning

confidence: 99%

Posttransplant Recurrence of Primary Glomerulonephritis

Ponticelli

Glassock

2010

Clinical Journal of the American Society of Nephrology

213

166

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All forms of primary GN may recur after kidney transplantation and potentially jeopardize the survival of the graft. IgA nephritis (IgAN) may recur in approximately one third of patients, more frequently in younger patients and in those with a rapid progression of the original disease. However, with the exception of few patients with rapid progression, there is no evidence that recurrence of IgAN has a deleterious effect on graft survival at least up to 10 years. Recurrence of focal segmental glomerulosclerosis (FSGS) is often associated with nephrotic proteinuria and is more frequent in children, in patients with rapid progression of the original disease, and in those who lost a previous transplant from recurrence. The natural course of recurrent FSGS is usually unfavorable. Early and intensive plasmapheresis may obtain complete or partial response in several patients. Good results have also been reported with rituximab. Idiopathic membranous nephropathy (IMN) may recur in 30% to 40% of patients. The graft survival in patients with IMN is not different than that of patients with other renal diseases. Good results with rituximab have been reported. Membranoproliferative GN (MPGN) may recur in 27% to 65% of patients. The recurrence is more frequent and the prognosis is more severe in type II MPGN. Although recurrent GN is relatively frequent and may worsen the outcome of renal allografts in some patients, its effect is diluted by several other risk-factors that may have a greater effect than recurrent GN on the long-term graft survival.

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Progression of renal allograft histology after renal transplantation in recurrent and nonrecurrent immunoglobulin A nephropathy

Cited by 14 publications

References 22 publications

Immunoglobulin A (IgA) Nephropathy in Protocol Graft Kidney Biopsy done at six months Post Transplantation in a Tertiary Care Center Hospital of Nepal

Immunoglobulin A (IgA) Nephropathy in Protocol Graft Kidney Biopsy done at six months Post Transplantation in a Tertiary Care Center Hospital of Nepal

Diagnosis of renal transplant rejection: Banff classification and beyond

Posttransplant Recurrence of Primary Glomerulonephritis

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