Progression of Renal Insufficiency in Children and Adolescents With Neuropathic Bladder is Not Accelerated by Lower Urinary Tract Reconstruction

Abstract

In our series bladder augmentation did not appear to hasten progression to end stage renal disease in patients with severe chronic renal insufficiency and neuropathic bladder.

Augmentation cystoplasty: Urodynamic and metabolic outcomes at 10‐year follow‐up

“…Significant renal impairment is a controversial contraindication for cystoplasty . Pediatric studies in patients with chronic renal impairment showed no significant change in renal function after cystoplasty, although the follow up was just 1.9 years . Other studies, including the current series, showed conflicting results.…”

The past, present and future of augmentation cystoplasty

“…Significant renal impairment is a more controversial relative contraindication. Recent studies of children with chronic renal insufficiency (mean GFR 34 mL/min/1.73m 2 ) and neuropathic bladders undergoing AC, showed no change in renal function at 1.9‐year follow‐up in 73%, and improvement in 18% [50].…”

Midterm outcomes of protection for upper urinary tract function by augmentation enterocystoplasty in patients with neurogenic bladder

“…Ninety-five ureters with UUTD, 96 ureters with VUR and 61 patients with chronic renal failure had a midterm It is widely accepted that significant renal impairment is a more controversial relative contraindication to AE [2,13]. A recent report suggested that AE does not hasten the progression of renal insufficiency in NBD patients [14]. In the current study, we observed the different outcomes.…”