Progressive diffuse meningioangiomatosis: Response to bevacizumab treatment

Yust‐Katz, Shlomit; Fuller, Gregory N.; Fichman-Horn, Suzana; Michaeli, Natalia; Inbar, Edna; Lukman, Judith; Limon, Dror; Steiner, Israel; Siegal, Tali

doi:10.1212/wnl.0000000000002610

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…However patients may experience recurrence because of incomplete evacuation [ 28 ], neoplastic malignancy [ 12 ], or coexisting with other malignant tumors [ 20 , 21 ]. In addition to surgery, medical treatment and follow-up observations have been reported [ 1 , 29 , 30 , 31 ]. Shlomit et al [ 29 ] reported a 67-year-old man with diffuse meningioma involving the occipital and right temporal lobes.…”

Section: Discussionmentioning

confidence: 99%

“…In addition to surgery, medical treatment and follow-up observations have been reported [ 1 , 29 , 30 , 31 ]. Shlomit et al [ 29 ] reported a 67-year-old man with diffuse meningioma involving the occipital and right temporal lobes. After being diagnosed with MA by biopsy, the patient benefited from antiangiogenic therapy with bevacizumab, which led to clinical stability and marked radiological improvement.…”

Section: Discussionmentioning

confidence: 99%

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Meningioangiomatosis Combined with Calcifying Pseudoneoplasms of Neuraxis

Sun

Cai

et al. 2023

Brain Sciences

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Meningioangiomatosis (MA) is a rare hamartomatous or meningovascular lesion involving the central nervous system, and is sometimes associated with intracranial meningiomas. Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, slow-growing benign tumor-like lesions that can occur anywhere along the neuraxis. Here, we report a rare case of MA combined with CAPNON. A 31-year-old woman was admitted to our hospital because of a high-density mass in the left frontal lobe, detected by computed tomography (CT) during a physical examination. She had a 3-year history of obsessive–compulsive disorder. We describe the imaging, histopathological, and molecular characteristics of the patient. To our knowledge, this is the first report describing MA combined with CAPNON. We reviewed the literature on MA and CAPNON over the last decade and summarized the points for differential diagnosis and treatment. It is difficult to preoperatively distinguish between MA and CAPNON. However, this coexisting condition should be considered when intra-axial calcification lesions are observed on radiological imaging. Accurate diagnosis and appropriate treatment are likely to benefit this patient group.

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