2023
DOI: 10.36416/1806-3756/e20230098
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Progressive fibrotic interstitial lung disease

Abstract: Many interstitial lung diseases (ILDs) share mechanisms that result in a progressive fibrosing phenotype. In Brazil, the most common progressive fibrosing interstitial lung diseases (PF-ILDs) are chronic hypersensitivity pneumonitis, idiopathic pulmonary fibrosis, unclassified ILD, and connective tissue diseases. PF-ILD is seen in approximately 30% of patients with ILD. Because PF-ILD is characterized by disease progression after initiation of appropriate treatment, a diagnosis of the disease resulting in fibr… Show more

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Cited by 1 publication
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“…Since there is no global consensus to stratify subjects with IPF according to the disease severity, we based this classification on a study by Antoniou et al [19] which used the FVC in % of predicted values to classify severity, so that subjects with an FVC below 50% of predicted values were classified as severe-to-very-severe IPF, and those above this value as mild-to-moderate disease. These values have been used by other studies, especially because they relate to severe physiological impairments [20] and also the risk for disease progression in this population [21].…”
Section: Methodsmentioning
confidence: 99%
“…Since there is no global consensus to stratify subjects with IPF according to the disease severity, we based this classification on a study by Antoniou et al [19] which used the FVC in % of predicted values to classify severity, so that subjects with an FVC below 50% of predicted values were classified as severe-to-very-severe IPF, and those above this value as mild-to-moderate disease. These values have been used by other studies, especially because they relate to severe physiological impairments [20] and also the risk for disease progression in this population [21].…”
Section: Methodsmentioning
confidence: 99%