Progressive Focal Deficit With Porencephaly

Leahy, William R.; Singer, Harvey S.

doi:10.1001/archneur.1977.00500150040007

Cited by 12 publications

(5 citation statements)

References 9 publications

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“…The most common clinical signs in human beings associated with these defects are spastic paresis and seizures. Clinical signs may be absent at birth but subsequently occur in an additive fashion (Leahy and Singer 1977) and may not begin for many years (Naef 1958). These pathological conditions have rarely been reported in dogs.…”

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confidence: 99%

Porencephaly and hydranencephaly in six dogs

et al. 2012

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A retrospective study was performed to identify dogs with cerebrospinal fluid-filled cavitatory lesions on MRI. Six dogs were included and the lesions were classified. In the three dogs in the present study with hydranencephaly, unilateral but complete loss of the temporal and parietal lobes was noted and had almost complete loss of the occipital and frontal lobes of a cerebral hemisphere. In the three dogs with porencephaly, there was unilateral incomplete loss of the parietal lobe and one dog had additional partial loss of the temporal and frontal lobes. Two of the dogs with porencephaly had seizures; the third showed no associated clinical signs. The dogs with hydranencephaly had mentation changes and circled compulsively. The two porencephalic dogs with seizures were treated with phenobarbitone. One of the dogs with hydranencephaly showed increased frequency and duration of circling; one dog's clinical signs did not progress and the third dog was euthanased due to increasing aggression. The dog with increased circling had ventriculoperitoneal shunt placement and the circling frequency reduced.

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Porencephaly and hydranencephaly in six dogs

et al. 2012

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“…The pathogenetic hypothesis of intraparenchymal ventricular diverticula is still debatable. 3–5 Intraparenchymal ventricular diverticula are known to occur in patients with chronic obstructive hydrocephalus without an identifiable focal surgical, vascular or traumatic etiology. 3 Intraparenchymal ventricular diverticulum refers to focal outpouching of the ventricle lined by a prolapsed ependymal layer that typically resolves after treating the hydrocephalus.…”

Section: Discussionmentioning

confidence: 99%

Ventricular pseudodiverticula from intraparenchymal cerebrospinal fluid dissection secondary to high-grade obstructive hydrocephalus in children: magnetic resonance imaging findings

2017

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We report on a series of three children who presented with a focal cerebrospinal fluid collection within the periventricular white matter of the temporal and occipital lobes in the setting of high-grade obstructive hydrocephalus. Magnetic resonance imaging showed a focal defect within the ventricular wall associated with leakage of cerebrospinal fluid into the adjacent white matter. The white matter tracts appeared primarily displaced. This entity should be referred to as ventricular pseudodiverticulum, not lined by ependymal cells, in contrast to a true ventricular diverticulum in which the cerebrospinal fluid is contained by a focal outpouching of the intact ventricular wall lined by a dilated and prolapsed layer of ependymal cells. Correct interpretation and classification of the findings may be helpful in predicting prognosis and outcome.

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“…We perform the derivation of the cyst to either the atrium or the peri toneum which produces the disappearance of cranial asymmetry, improvement of the signs of motor deficit and of the ocular motor nerves, a marked improvement in the thickness of the cerebral parenchyma surrounding the CPC by diminishing the intraventricular and intracystic pressure [6,16,18,26,28] (fig. 2, 3).…”

Section: Discussionmentioning

confidence: 99%

“…We are of the opinion that the mental ability and social behavior are improved since we have read that children not subjected to surgery exhibit a progressive mental deterioration according to the experience of Leahy and Singer [16] …”

Section: Discussionmentioning

confidence: 99%

“…These cavities begin during early fetal development, an origin which has been controversial [18], as a focal encephalic malformation compo nent of a diffuse cerebral maldevelopment, different from the poren- ceplialy acquired following trauma, infections, vascular disease, or degen erative disease [16,18,26], The association of porencephalic cysts with hydrocephalus was first described by Northfield and Russell [ 19] in 1939. This report describes 10 patients with hydrocephalus, retarded psychomotor development, seizures and progressive focal motor deficit secondary to porencephalic diverticulation of the lateral ventricles.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Porencephalic Congenital Cysts with Hydrocephalus

Suárez¹,

Sfaello²,

Albarenque³

et al. 1984

Pediatr Neurosurg

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The therapeutic criteria according to tomographic findings are reviewed. 10 children, 6 male and 4 female, with porencephalic congenital cysts were studied. Early symptoms began within the first 6 months of life in 9 cases, and at the age of 5 years in 1. The most frequent symptoms were: seizures in 3; motor deficit in 5; retarded psychomotor development in 7; endocranial hypertension syndrome in 7; symmetric macrocrania in 7; paresis ofthe motor ocular nerves in 4. Preoperative studies: (1) X-ray films- 1 each patient – showed diastasis of sutures in 6 and cranial asymmetry in 2. (2) Electroencephalograms – 6 patients

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Progressive Focal Deficit With Porencephaly

Cited by 12 publications

References 9 publications

Porencephaly and hydranencephaly in six dogs

Porencephaly and hydranencephaly in six dogs

Ventricular pseudodiverticula from intraparenchymal cerebrospinal fluid dissection secondary to high-grade obstructive hydrocephalus in children: magnetic resonance imaging findings

Porencephalic Congenital Cysts with Hydrocephalus

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