Progressive lymphocytic-plasmocytic enteritis in a horse

Siwińska, Natalia; Żak, Agnieszka; Słowikowska, Malwina; Borowicz, Hieronim; Nowak, Marcin; Ciaputa, Rafał; Kubiak, Krzysztof; Niedźwiedź, Artur

doi:10.21836/pem20170505

Cited by 2 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of the 149 horses in the present study, 117 (78.5%) suffered from LPE. This contradicts the earlier literature, which suggested that LPE is the least common form of IBD in horses [1,14]. Until 2017, only 24 cases of LPE had been reported [13,14,19,23,[36][37][38].…”

Section: Discussionmentioning

confidence: 92%

“…This contradicts the earlier literature, which suggested that LPE is the least common form of IBD in horses [1,14]. Until 2017, only 24 cases of LPE had been reported [13,14,19,23,[36][37][38]. A more recent study found another 16 horses with LPE out of 37 horses with IBD in which a duodenal biopsy was taken [5].…”

Section: Discussionmentioning

confidence: 95%

“…In the more recent literature, however, it appears that LPE is the most common form of IBD [ 5 , 12 ]. LPE causes weight loss, variable diarrhea, depression, recurrent colic and inappetence [ 2 , 13 , 14 ]. The mucosal infiltration of lymphocytes and plasma cells, without granulomatous changes and villous atrophy, can be found using a histopathological examination of the affected intestine [ 2 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…LPE causes weight loss, variable diarrhea, depression, recurrent colic and inappetence [ 2 , 13 , 14 ]. The mucosal infiltration of lymphocytes and plasma cells, without granulomatous changes and villous atrophy, can be found using a histopathological examination of the affected intestine [ 2 , 14 ]. However, these cells can also be found with many other intestinal diseases [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Findings and Prognosis in 149 Horses with Histological Changes Compatible with Inflammatory Bowel Disease

Kranenburg,

Bouwmeester,

van den Boom

2024

Animals

View full text Add to dashboard Cite

Inflammatory bowel disease (IBD) is a chronic disease characterized by different cell infiltrates in the intestine. The aims of this study were to report the clinical and clinicopathological findings in horses with histological changes compatible with IBD in the duodenum. Further, the clinical progression of IBD and survival were investigated. Patient records were reviewed for horses in which histological evidence of IBD was found in duodenal biopsies collected during endoscopy. The histological changes were classified as mild, moderate or severe and the predominant infiltrating cell type was recorded. Clinical improvement was assessed by the owner via a questionnaire at 6 weeks after biopsy, along with survival after one year. In total, 149 horses were included, and the most common clinical signs were weight loss, reduced performance and pain during abdominal palpation. Most horses showed partial malabsorption during an oral glucose absorption test, and the horses with severe IBD had lower serum protein concentrations. Lymphoplasmacytic enteritis was the most common type of IBD (78.5% of cases), while in six horses neutrophilic infiltration of the duodenum was present. Overall, 71% of the cases had improved clinically after six weeks, mostly following treatment with corticosteroids. The results of a second biopsy were a poor predictor of improvement, and the horses that improved after 6 weeks were more likely to be alive after one year.

show abstract

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Findings and Prognosis in 149 Horses with Histological Changes Compatible with Inflammatory Bowel Disease

Kranenburg,

Bouwmeester,

van den Boom

2024

Animals

View full text Add to dashboard Cite

show abstract

“…Although, due to the high suspicion of inflammatory bowel disease, treatment with corticosteroids and diet changes were recommended. Intramuscular dexamethasone sodium phosphate injections were administered at a dosage of 0,1 mg/kg SID for 7 days followed by 0,05 mg/kg SID for 7 days [9,10].…”

Section: Case Historymentioning

confidence: 99%

Lymphocytic-Plasmacytic Enteritis as a Cause of Long-Lasting Weight Loss and Recurrent Colic in an Elderly Horse

Barros¹,

Oliveira²,

Campos

et al. 2021

BJSTR

View full text Add to dashboard Cite

Lymphocytic-Plasmacytic Enteritis (LPE) is an uncommon cause of chronic inflammatory bowel disease in horses. The proliferative inflammatory cell infiltrate results in diffuse mucosal inflammation and impaired nutrients absorption, leading to chronic weight loss, recurrent abdominal pain and hypoproteinemia. This article reports the case of a 25-year-old horse with LPE causing long-lasting severe cachexia and recurrent colic episodes. A positive response to diet changes and medical treatment with corticosteroids was observed during a short period of time. However, relapse of recurrent colic episodes refractory to medical treatment determined the euthanasia of the horse.

show abstract

Progressive lymphocytic-plasmocytic enteritis in a horse

Cited by 2 publications

References 12 publications

Findings and Prognosis in 149 Horses with Histological Changes Compatible with Inflammatory Bowel Disease

Findings and Prognosis in 149 Horses with Histological Changes Compatible with Inflammatory Bowel Disease

Lymphocytic-Plasmacytic Enteritis as a Cause of Long-Lasting Weight Loss and Recurrent Colic in an Elderly Horse

Contact Info

Product

Resources

About