Progressive motor deficits in lacunar infarction

Abstract

The progression of motor deficits is associated with a relatively poor functional outcome. Diabetes mellitus and the severity of motor deficit on admission may predict progression of motor deficits.

Multimodal CT Provides Improved Performance for Lacunar Infarct Detection

“…The frequency and significance of perfusion abnormality in LI was previously addressed in several small series. [26][27][28] One of the largest studies (22 patients) demonstrated MTT abnormality in 68.2% of LIs, comparing favorably with 61% in the present series.…”

Induced-hypertension in progressing lacunar infarction

“…There has been no clear explanation on the mechanism of progressing lacunar infarction and motor recovery after induced hypertension [5,[22][23][24][25]. Nevertheless, there is a case report of the benefit of induced-hypertension, which early neurological deterioration due to perfusion defect in a progressing large artery territory infarction was restored [6].…”

Efficacy of Edaravone, a Free Radical Scavenger, for the Treatment of Acute Lacunar Infarction

“…Patients with lacunar infarction have a better prognosis than those with other stroke subtypes, 20) although neurological deterioration was observed in 20-40% of patients with acute lacunar infarction. 18,22,24,25) Effective therapy for patients with lacunar infarction is very desirable, because they are likely to return to normal lives. Edaravone is a promising radical scavenger for the treatment of such patients with acute lacunar stroke.…”