Progressive Skin Depressions in a Child’s Neck

Abstract

A 2-year-old girl who was otherwise healthy presented with a 10-month history of asymptomatic skin depressions in her neck, nape, and submandibular regions. The lesion initially occurred as an erythema in the neck and progressed centrifugally to the nape and submandibular areas. Atrophy was observed in the center of the lesion, surrounded by an erythematous border, with underlying blood vessels being visible deep to the atrophy (Figure , A).Cervical lymph nodes were palpable bilaterally. Tactile responses within the depressed as well as surrounding areas were normal. Other physical examinations were without abnormalities. Her medical and family histories were unremarkable. Her parents denied drug injection or trauma history. Results of routine laboratory tests, HIV test, serological test of antibodies for Borrelia, and antinuclear antibody test were within normal limits or negative. After obtaining informed consent from her parents, a biopsy specimen was taken from the edge of the depressed lesion for histological examination.

Clinicopathological characteristics, treatment and follow‐up of lipodystrophia centrifugalis abdominalis infantilis: A retrospective case series in China

“…The depressed lesions could enlarge centrifugally to the neighbouring areas. 2,3 In this study, we conducted a retrospective review to analyse the clinicopathological characteristics, treatment outcomes and prognosis of 127 patients in China.…”

“…It is characterized by a depression with a periphery of erythema present on the lower abdomen and/or the groin region, axilla or neck. The depressed lesions could enlarge centrifugally to the neighbouring areas 2,3 . In this study, we conducted a retrospective review to analyse the clinicopathological characteristics, treatment outcomes and prognosis of 127 patients in China.…”